Are there studies that compare overall mortality between HHD to PD?
There are few comparative effectiveness studies to help better answer this question.
One of the first studies to examine this was an observational cohort analysis using the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA).
The primary outcome of mortality between conventional in-center dialysis, PD, and HHD was examined with all patients starting dialysis over a 1-year period.
home hemodialysis had a 49% lower mortality rate when compared with patients receiving conventional in-center HD.
In contrast, patients receiving PD had similar mortality as the conventional in-center HD cohort. However, patients in the home hemodialysis group were younger, with fewer comorbid conditions, and hence “healthier” than their PD and in-center HD counterparts.