Potential advantages of 90 Y radioembolization compared with TACE
90 Y radioembolization has a decreased incidence and severity of PES and thus can be performed as an outpatient procedure without the need for hospitalization. Recent studies suggest better disease control (longer time to progression) with less toxicity with 90 Y radioembolization than TACE, although no survival differences between the two treatments have been demonstrated. Additionally, 90 Y radioembolization for HCC (TheraSpheres) is a microembolic procedure causing minimal occlusion of the hepatic arteries and may be safely used in the setting of portal vein thrombosis.