What medications have uricosuric effect

What medications have uricosuric effect even if not prescribed for this reason?

  • Losartan: modest uricosuric effect, plateaus at 50 mg daily.
  • Fenofibrate: may induce ∼20% decrease in serum uric acid.
  • Atorvastatin (note the risk of myopathy with statins + fibrates).
  • High-dose (>4 g/day) salicylates.

Pearl: consider choosing medications with urate-lowering “side effect” for patients with gout and comorbid hypertension or dyslipidemia.

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856