Sodium Tetradecyl Sulfate (Sotradecol)

What is Sodium Tetradecyl Sulfate

Sodium tetradecyl sulfate is an injectable sclerosing agent indicated for the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves.

The benefit-to-risk ratio should be considered in selected patients who are great surgical risks.

Sodium tetradecyl sulfate should only be administered by a health care professional experienced in venous anatomy and the diagnosis and treatment of conditions affecting the venous system and familiar with proper injection technique.

Severe adverse local effects, including tissue necrosis, may occur after extravasation.

Brand Name


Indications & Dosage

  • esophageal varices
  • upper GI bleeding
  • variceal bleeding
  • varicose veins

Side Effects

  1. air embolism
  2. anaphylactic shock
  3. headache
  4. injection site reaction
  5. myocardial infarction
  6. nausea
  7. pulmonary embolism
  8. skin discoloration
  9. skin ulcer
  10. stroke
  11. thromboembolism
  12. tissue necrosis
  13. urticaria
  14. vomiting

Monitoring Parameters

  • laboratory monitoring not necessary


  • air embolism
  • asthma
  • breast-feeding
  • diabetes mellitus
  • extravasation
  • hematological disease
  • infection
  • neoplastic disease
  • pregnancy
  • pulmonary disease
  • requires an experienced clinician
  • sepsis
  • skin disease
  • thromboangiitis obliterans (Buerger’s disease)
  • thrombophlebitis
  • thyrotoxicosis
  • tuberculosis


There are no drug interactions associated with Sodium Tetradecyl Sulfate products.


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