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What is Sodium Lactate
Sodium lactate is a parenteral alkalizing agent used in the management of mild to moderate metabolic acidosis.
Sodium lactate and other bicarbonate precursors are used to overcome the chemical and physical incompatibilities associated with administration of parenteral bicarbonate.
Sodium lactate was approved by the FDA in March 1971.
Indications & Dosage
- metabolic acidosis
- urinary alkalinization
For the prevention and treatment of mild to moderate metabolic acidosis
Side Effects
- anaphylactoid reactions
- angioedema
- edema
- erythema
- fever
- hypernatremia
- hypervolemia
- hypokalemia
- hypotension
- infusion-related reactions
- injection site reaction
- metabolic alkalosis
- phlebitis
- pruritus
- tissue necrosis
- urticaria
Monitoring Parameters
- arterial blood gases (ABGs)
- serum bicarbonate
- serum sodium
Contraindications
- beriberi
- breast-feeding
- geriatric
- heart failure
- hepatic disease
- hypernatremia
- hypokalemia
- hypoxemia
- lactic acidosis
- pregnancy
- renal disease
- renal failure
- renal impairment
- shock
Interactions
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Pseudoephedrine
- Acrivastine; Pseudoephedrine
- Amphetamines
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Brompheniramine; Pseudoephedrine
- Carbetapentane; Pseudoephedrine
- Carbinoxamine; Dextromethorphan; Pseudoephedrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carbinoxamine; Pseudoephedrine
- Cetirizine; Pseudoephedrine
- Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Pseudoephedrine
- Chlorpropamide
- Choline Salicylate; Magnesium Salicylate
- Colchicine
- Colchicine; Probenecid
- Desloratadine; Pseudoephedrine
- Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
- Dextromethorphan; Guaifenesin; Pseudoephedrine
- Dextromethorphan; Quinidine
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Donepezil; Memantine
- Fexofenadine; Pseudoephedrine
- Flecainide
- food
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Guaifenesin; Pseudoephedrine
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibuprofen; Pseudoephedrine
- Lithium
- Loratadine; Pseudoephedrine
- Magnesium Salicylate
- Memantine
- Methenamine
- Methenamine; Sodium Acid Phosphate
- Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
- Naproxen; Pseudoephedrine
- Pseudoephedrine
- Quinidine
- Salsalate
