Simethicone

What is Simethicone

Simethicone is an oral antiflatulent agent.

It is used to relieve the pain and pressure of excess gas in the digestive tract.

Indications & Dosage

• bowel preparation
• dyspepsia
• flatulence
• gastrointestinal radiography

For the symptomatic relief of pressure, bloating, and fullness commonly referred to as gas (flatulence)

Side Effects

• eructation
• flatulence

Troublesome adverse events reported with simethicone are infrequent; the more common and mild side effects include eructation and flatulence as air bubbles and gas are eliminated from the GI tract. The drug is not absorbed systemically.

Monitoring Parameters

• laboratory monitoring not necessary

Contraindications

• breast-feeding
• phenylketonuria
• pregnancy

Interactions

• Levothyroxine
• Levothyroxine; Liothyronine (Porcine)
• Levothyroxine; Liothyronine (Synthetic)
• Liothyronine
• Thyroid hormones