Para Aminobenzoic Acid

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What is Para Aminobenzoic Acid

Para Aminobenzoic Acid is often used as an oral dietary supplement. Aminobenzoate potassium, an oral potassium salt of para-aminobenzoic acid (PABA), is an approved drug, the FDA considers the agent ‘possibly effective’ for chronic diseases involving fibrosis and nonsuppurative inflammation, such as scleroderma, dermatomyositis, morphea, linear scleroderma, pemphigus, and Peyronie’s disease.

More commonly, topical para-aminobenzoic acid (PABA) is used as a chemical sunscreen agent (see Sunscreens monograph) in combination with other sunscreens.

Indications

  • photoprotection

Side Effects

  1. acne vulgaris
  2. contact dermatitis
  3. erythema
  4. folliculitis
  5. pruritus
  6. skin discoloration
  7. skin irritation

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • breast-feeding
  • children
  • ester local anesthetic hypersensitivity
  • infants
  • pregnancy
  • skin disease
  • sulfonamide hypersensitivity
  • thiazide diuretic hypersensitivity
  • xeroderma pigmentosum

Interactions

No information is available regarding drug interactions associated with Para-Aminobenzoic Acid

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