Deoxycholic Acid

Deoxycholic Acid Brand Name– Kybella

What is Deoxycholic Acid

Deoxycholic acid is a cytolytic drug indicated for improvement in the appearance of moderate to severe convexity or fullness associated with submental fat in adults.

Safety and efficacy have not been established for use outside of the submental area or in adolescent patients.

Deoxycholic acid (Kybella) was approved by the FDA in April 2015.

Indications

  • submental fat

For the improvement in the appearance of moderate to severe convexity or fullness associated with submental fat

Side Effects

  1. alopecia
  2. bleeding
  3. cranial nerve palsies
  4. dysphagia
  5. ecchymosis
  6. edema
  7. erythema
  8. headache
  9. hematoma
  10. hypertension
  11. hypoesthesia
  12. injection site reaction
  13. lymphadenopathy
  14. nausea
  15. paresis
  16. paresthesias
  17. pruritus
  18. skin discoloration
  19. skin necrosis
  20. skin ulcer
  21. syncope
  22. urticaria

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • anticoagulant therapy
  • bleeding
  • breast-feeding
  • cervical lymphadenopathy
  • children
  • coagulopathy
  • dysphagia
  • goiter
  • infants
  • infection
  • intraarterial administration
  • intramuscular administration
  • intravenous administration
  • pregnancy
  • surgery

Deoxycholic acid is contraindicated if signs of infection are presentat the injection sites.

Interactions

No information is available regarding drug interactions associated with Deoxycholic Acid

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