Nystatin

Nystatin Brand Names

Bio-Statin | Mycostatin | Nyamyc | Nyata | Nystex | Nystop | Pedi-Dri

What is Nystatin

Nystatin is a topical polyene antifungal antibiotic, similar in structure to amphotericin B. Regular nystatin is not used to treat systemic fungal infections because of its negligible absorption from the gastrointestinal tract.

Nystatin is most useful in the treatment of oropharyngeal, cutaneous, mucocutaneous, and vulvovaginal candidiasis.

Nystatin was approved by the FDA in 1954.

Indications

1. Candida albicans
2. Candida glabrata
3. Candida guilliermondii
4. Candida krusei
5. Candida parapsilosis
6. Candida pseudotropicalis
7. Candida sp.
8. Candida tropicalis
9. candidiasis
10. candidiasis prophylaxis
11. diaper dermatitis
12. mucocutaneous candidiasis
13. oropharyngeal candidiasis (thrush)
14. Trichophyton mentagrophytes
15. Trichophyton rubrum
16. vulvovaginal candidiasis

Side Effects

1. angioedema
2. bronchospasm
3. diarrhea
4. dyspepsia
5. eczema vaccinatum
6. hyperglycemia
7. myalgia
8. nausea
9. pruritus
10. rash
11. sinus tachycardia
12. skin irritation
13. Stevens-Johnson syndrome
14. urticaria
15. vomiting

Monitoring Parameters

• laboratory monitoring not necessary

Contraindications

• breast-feeding
• diabetes mellitus
• paraben hypersensitivity
• pregnancy

Interactions

• Econazole
• Ketoconazole
• Miconazole
• Miconazole; Petrolatum; Zinc Oxide
• Oxiconazole
• Sertaconazole
• Sulconazole