Nizatidine Brand Name– Axid | Axid AR
What is Nizatidine
Nizatidine is an oral H2-receptor antagonist. Nizatidine is indicated for gastroesophageal reflux disease (GERD), short-term and maintenance treatment of duodenal ulcer, and short-term treatment of active benign gastric ulcer.
A non-prescription (OTC) product is also available for self-treatment of pyrosis (heart burn), dyspepsia, and sour stomach. Of note, for the symptomatic acute and chronic treatment of GERD, proton pump inhibitors (PPIs) are considered to be more effective than H2-blockers.
Indications
- aspiration prophylaxis
- duodenal ulcer
- dyspepsia
- esophagitis
- gastric ulcer
- gastroesophageal reflux disease (GERD)
- pyrosis (heartburn)
- stress gastritis prophylaxis
For self-medication of pyrosis (heartburn), acid dyspepsia (acid indigestion), or sour stomach
Side Effects
- amblyopia
- anaphylactoid reactions
- anemia
- anxiety
- atrophic gastritis
- bronchospasm
- chest pain (unspecified)
- cholestasis
- confusion
- cough
- diarrhea
- dizziness
- drowsiness
- elevated hepatic enzymes
- eosinophilia
- exfoliative dermatitis
- fever
- gynecomastia
- headache
- hepatitis
- hyperuricemia
- impotence (erectile dysfunction)
- infection
- irritability
- jaundice
- laryngeal edema
- myalgia
- nasal congestion
- pernicious anemia
- pharyngitis
- pruritus
- purpura
- rash
- rhinitis
- seizures
- serum sickness
- sinusitis
- thrombocytopenia
- urticaria
- vasculitis
- ventricular tachycardia
- vitamin B12 deficiency
- vomiting
- xerostomia
Monitoring Parameters
- intragastric pH
- serum creatinine/BUN
Contraindications
- breast-feeding
- children
- dysphagia
- gastric cancer
- geriatric
- H2-blocker hypersensitivity
- infants
- infection
- neonates
- pregnancy
- renal failure
- renal impairment
- tobacco smoking
- vitamin B12 deficiency
Interactions
- Acalabrutinib
- Alendronate
- Alendronate; Cholecalciferol
- Amphetamine; Dextroamphetamine Salts
- Atazanavir
- Atazanavir; Cobicistat
- Bisacodyl
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bosutinib
- Budesonide
- Budesonide; Formoterol
- Calcium Carbonate; Risedronate
- Cefditoren
- Cefpodoxime
- Ceftibuten
- Cefuroxime
- Cysteamine
- Dacomitinib
- Dasatinib
- Delavirdine
- Dexmethylphenidate
- Diphenhydramine; Naproxen
- Dirithromycin
- Dolutegravir; Rilpivirine
- Emtricitabine; Rilpivirine; Tenofovir alafenamide
- Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
- Erlotinib
- Esomeprazole; Naproxen
- Ethanol
- Fosamprenavir
- Gefitinib
- Iron
- Itraconazole
- Ketoconazole
- Lansoprazole; Naproxen
- Ledipasvir; Sofosbuvir
- Mefloquine
- Mesalamine, 5-ASA
- Methylphenidate
- Naproxen
- Naproxen; Pseudoephedrine
- Naproxen; Sumatriptan
- Neratinib
- Nilotinib
- Octreotide
- Pazopanib
- Pexidartinib
- Polyethylene Glycol; Electrolytes; Bisacodyl
- Ponatinib
- Rilpivirine
- Risedronate
- Secretin
- Selpercatinib
- Sofosbuvir; Velpatasvir
- Sofosbuvir; Velpatasvir; Voxilaprevir
- Sonidegib
- Thalidomide
