Ocriplasmin

Ocriplasmin Brand Name– JETREA

What is Ocriplasmin

Ocriplasmin is a proteolytic enzyme approved for the treatment of symptomatic vitreomacular adhesion (VMA).

Ocriplasmin is administered via ophthalmic intravitreal injection only. This is the first drug to receive FDA-approval for the treatment of VMA.

Ocriplasmin (Jetrea) was approved by the FDA in October 2012.

Indications

  • vitreomacular adhesion

For the treatment of symptomatic vitreomacular adhesion

Side Effects

  1. blurred vision
  2. cataracts
  3. conjunctival hyperemia
  4. dyschromatopsia
  5. iritis
  6. lens subluxation
  7. macular edema
  8. night blindness
  9. ocular hemorrhage
  10. ocular hypertension
  11. ocular infection
  12. ocular inflammation
  13. ocular irritation
  14. ocular pain
  15. photophobia
  16. photopsia
  17. retinal detachment
  18. retinal edema
  19. visual impairment
  20. xerophthalmia

Monitoring Parameters

  • intraocular pressure

Contraindications

  • breast-feeding
  • children
  • glaucoma
  • infants
  • neonates
  • ocular infection
  • ocular surgery
  • pregnancy

Interactions

There are no drug interactions associated with Ocriplasmin products.

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