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Hydrocortisone Lidocaine Brand Names
Ana-Lex HC | AnaMantle HC | AnaMantle-HC Forte | LidaMantle HC | LidaZone HC | LidoCort | Lidosol-HC | Peranex HC | RectaGel HC | Senatec HC
What is Hydrocortisone Lidocaine
Hydrocortisone and lidocaine are combined and used topically and rectally for the relief of inflammation, pain, and pruritus associated with minor skin irritations, hemorrhoids, and anal fissures.
Hydrocortisone is a corticosteroid that has antiinflammatory, antipruritic, and vasoconstrictive properties; lidocaine is a topical amide local anesthetic that provides relief of pain and itching.
Several different formulations are available, including creams, gels, and lotions; these combinations are for prescription use only.
Hydrocortisone and lidocaine were initially marketed for use before 1962, which is when Congress passed the amended Federal Food, Drug, and Cosmetic Act requiring that the FDA establish both safety and efficacy for all subsequently approved drugs.
Hydrocortisone lidocaine is an unapproved marketed drug that has not been formally evaluated by the FDA.
Indications
- anal fissures
- burns
- eczema
- hemorrhoids
- insect bites or stings
- mild pain
- pruritus
- skin abrasion
For the treatment of mild pain and pruritus due to pruritic eczema, skin abrasion, minor burns, insect bites or stings, and similar conditions of the skin and mucous membranes.
Side Effects
- acneiform rash
- adrenocortical insufficiency
- confusion
- contact dermatitis
- Cushing’s syndrome
- dizziness
- erythema
- folliculitis
- glycosuria
- growth inhibition
- hyperglycemia
- hypertrichosis
- hypotension
- hypothalamic-pituitary-adrenal (HPA) suppression
- increased intracranial pressure
- infection
- methemoglobinemia
- miliaria
- palpitations
- pruritus
- seizures
- skin atrophy
- skin hypopigmentation
- skin irritation
- striae
- tremor
- xerosis
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- accidental exposure
- amide local anesthetic hypersensitivity
- breast-feeding
- cardiac disease
- children
- corticosteroid hypersensitivity
- Cushing’s syndrome
- diabetes mellitus
- fungal infection
- G6PD deficiency
- geriatric
- growth inhibition
- hepatic disease
- herpes infection
- hypothalamic-pituitary-adrenal (HPA) suppression
- increased intracranial pressure
- infants
- infection
- methemoglobinemia
- neonates
- occlusive dressing
- ocular exposure
- pregnancy
- pulmonary disease
- skin abrasion
- skin atrophy
- tuberculosis
- varicella
- viral infection
Interactions
- Adapalene; Benzoyl Peroxide
- Benzoyl Peroxide
- Benzoyl Peroxide; Clindamycin
- Benzoyl Peroxide; Erythromycin
- Benzoyl Peroxide; Sulfur
- Chloroxylenol; Hydrocortisone; Pramoxine
- Dibucaine
- Ethyl Chloride
- Hydrocortisone; Pramoxine
- Pramoxine