Is there an easy method to calculate mixtures of constant infusions of drugs?
Several methods are used. Here is one easy method:
- • For constant infusion of drugs (epinephrine, isoproterenol) beginning at 0.1 μg/kg/minute : 0.6 times the weight (in kg) equals the number of milligrams of drug to add to enough water to make a total of 100 mL of solution. The resultant solution is then infused at a rate of 1 mL/hour, delivering 0.1 μg/kg/minute.
- • For constant infusion of drugs (dopamine, dobutamine) beginning at 1 μg/kg/minute : 6 times the weight (in kg) equals the number of milligrams of drug to add to enough water to make a total of 100 mL of solution. The resultant solution is then infused at a rate of 1 mL/hour, delivering 1 μg/kg/minute.
