Do some NSAIDs inhibit COX 1 or COX 2 preferentially?
Yes. A classification system is listed below according to the NSAID ability to inhibit COX-1 and/or COX-2 in therapeutic doses.
Nomenclature | NSAIDs in this Classification |
COX-1 selective | Low-dose ASA (irreversibly binds to serine 530 on COX-1) |
COX nonselective | Ibuprofen, naproxen, meclomen, indomethacin |
COX-2 selective | Etodolac, diclofenac, nabumetone, meloxicam |
COX-2 highly selective | Celecoxib |