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Diazepam Brand Names
Diastat | Dizac | Valium | VALTOCO
What is Diazepam
Diazepam is an oral, nasal, parenteral, or rectal long-acting benzodiazepine indicated for anxiety, acute alcohol withdrawal, skeletal muscle spasm, and seizure disorders, including status epilepticus.
Diazepam may be used adjunctively for skeletal muscle spasms and seizure disorders; it has not been proven useful as sole therapy in epilepsy.
As an adjunct or premedication before procedures like surgery or endoscopy, diazepam may relieve apprehension or acute stress and diminish patient recall of the procedure.
Like with other benzodiazepines, concomitant use of diazepam with opioids may result in profound sedation, respiratory depression, coma, and death.
Indications
- acute repetitive seizures
- alcohol withdrawal
- amnesia induction
- anxiety
- benzodiazepine withdrawal
- chloroquine overdose
- insomnia
- muscle spasm
- partial seizures
- procedural sedation
- status epilepticus
- tetanus
- tonic-clonic seizures
For the treatment of anxiety disorders or for the short-term relief of the symptoms of anxiety
Side Effects
- abdominal pain
- agitation
- amnesia
- anemia
- anorexia
- anxiety
- apnea
- appetite stimulation
- ataxia
- blurred vision
- bone fractures
- bradycardia
- cardiac arrest
- chest pain (unspecified)
- confusion
- constipation
- cough
- depression
- diaphoresis
- diarrhea
- diplopia
- dizziness
- drowsiness
- dysarthria
- dysgeusia
- dyspnea
- elevated hepatic enzymes
- emotional lability
- epistaxis
- euphoria
- fatigue
- hallucinations
- headache
- hiccups
- hyperkinesis
- hypersalivation
- hyperventilation
- hypotension
- infection
- injection site reaction
- insomnia
- irritability
- jaundice
- laryngospasm
- libido decrease
- libido increase
- lymphadenopathy
- mania
- memory impairment
- menstrual irregularity
- myasthenia
- mydriasis
- nasal congestion
- nasal irritation
- nausea
- neutropenia
- nightmares
- nystagmus
- peripheral vasodilation
- phlebitis
- physiological dependence
- pruritus
- psychological dependence
- rash
- respiratory depression
- restlessness
- rhinitis
- seizures
- syncope
- thrombosis
- tolerance
- tremor
- urinary incontinence
- urinary retention
- urticaria
- vertigo
- vomiting
- weight gain
- weight loss
- withdrawal
- xerostomia
Monitoring Parameters
- CBC
- LFTs
Contraindications
- abrupt discontinuation
- asthma
- breast-feeding
- children
- closed-angle glaucoma
- CNS depression
- coadministration with other CNS depressants
- coma
- dementia
- depression
- driving or operating machinery
- ethanol ingestion
- ethanol intoxication
- extravasation
- geriatric
- hepatic disease
- infants
- intraarterial administration
- labor
- myasthenia gravis
- neonates
- neutropenia
- obstetric delivery
- pregnancy
- psychosis
- pulmonary disease
- renal disease
- renal failure
- renal impairment
- respiratory depression
- respiratory insufficiency
- seizure disorder
- shock
- sleep apnea
- status epilepticus
- suicidal ideation
Interactions
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan; Doxylamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Diphenhydramine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Propoxyphene
- Acetaminophen; Tramadol
- Acrivastine; Pseudoephedrine
- Aldesleukin, IL-2
- Alfentanil
- Alprazolam
- Aluminum Hydroxide
- Aluminum Hydroxide; Magnesium Carbonate
- Aluminum Hydroxide; Magnesium Hydroxide
- Aluminum Hydroxide; Magnesium Hydroxide; Simethicone
- Aluminum Hydroxide; Magnesium Trisilicate
- Amiodarone
- Amobarbital
- Amoxapine
- Amoxicillin; Clarithromycin; Lansoprazole
- Amoxicillin; Clarithromycin; Omeprazole
- Amphetamine; Dextroamphetamine Salts
- Antacids
- Apalutamide
- Apomorphine
- Apraclonidine
- Aprepitant, Fosaprepitant
- Aripiprazole
- Armodafinil
- Asenapine
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Atazanavir; Cobicistat
- Atracurium
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Azelastine
- Azelastine; Fluticasone
- Bacitracin
- Barbiturates
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Benzhydrocodone; Acetaminophen
- Benztropine
- Boceprevir
- Bosentan
- Brimonidine
- Brimonidine; Brinzolamide
- Brimonidine; Timolol
- Brompheniramine
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Dextromethorphan; Guaifenesin
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Brompheniramine; Pseudoephedrine
- Buprenorphine
- Buprenorphine; Naloxone
- Buspirone
- Butabarbital
- Butorphanol
- Caffeine
- Caffeine; Ergotamine
- Calcium Carbonate
- Calcium Carbonate; Magnesium Hydroxide
- Calcium Carbonate; Risedronate
- Calcium Carbonate; Simethicone
- Cannabidiol
- Carbamazepine
- Carbetapentane; Chlorpheniramine
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbetapentane; Pseudoephedrine
- Carbetapentane; Pyrilamine
- Carbinoxamine
- Carbinoxamine; Dextromethorphan; Pseudoephedrine
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carbinoxamine; Phenylephrine
- Carbinoxamine; Pseudoephedrine
- Cariprazine
- Cenobamate
- Ceritinib
- Cetirizine
- Cetirizine; Pseudoephedrine
- Chlophedianol; Dexbrompheniramine
- Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
- Chlophedianol; Guaifenesin; Phenylephrine
- Chlorcyclizine
- Chlorpheniramine
- Chlorpheniramine; Codeine
- Chlorpheniramine; Dextromethorphan
- Chlorpheniramine; Dextromethorphan; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Phenylephrine
- Chlorpheniramine; Pseudoephedrine
- Chlorthalidone; Clonidine
- Cimetidine
- Ciprofloxacin
- Cisapride
- Cisatracurium
- Citalopram
- Clarithromycin
- Clemastine
- Clobazam
- Clonidine
- Clozapine
- Cobicistat
- Codeine
- Codeine; Guaifenesin
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- Colchicine; Probenecid
- Colesevelam
- COMT inhibitors
- Conivaptan
- Crizotinib
- Cyclizine
- Cyproheptadine
- Dalfopristin; Quinupristin
- Danazol
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Delavirdine
- Desflurane
- Deutetrabenazine
- Dexchlorpheniramine
- Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
- Dexmedetomidine
- Dextromethorphan; Diphenhydramine; Phenylephrine
- Dextromethorphan; Guaifenesin; Phenylephrine
- Dicyclomine
- Digoxin
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Diltiazem
- Dimenhydrinate
- Diphenhydramine
- Diphenhydramine; Hydrocodone; Phenylephrine
- Diphenhydramine; Ibuprofen
- Diphenhydramine; Naproxen
- Diphenhydramine; Phenylephrine
- Disulfiram
- Doxacurium
- Doxylamine
- Doxylamine; Pyridoxine
- Dronabinol
- Dronedarone
- Droperidol
- Drospirenone; Ethinyl Estradiol
- Drospirenone; Ethinyl Estradiol; Levomefolate
- Efavirenz
- Efavirenz; Emtricitabine; Tenofovir
- Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
- Elagolix
- Elbasvir; Grazoprevir
- Elexacaftor; tezacaftor; ivacaftor
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Enflurane
- Enzalutamide
- Erythromycin
- Erythromycin; Sulfisoxazole
- Escitalopram
- Esketamine
- Esomeprazole
- Esomeprazole; Naproxen
- Eszopiclone
- Ethanol
- Ethinyl Estradiol
- Ethinyl Estradiol; Desogestrel
- Ethinyl Estradiol; Ethynodiol Diacetate
- Ethinyl Estradiol; Etonogestrel
- Ethinyl Estradiol; Levonorgestrel
- Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
- Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
- Ethinyl Estradiol; Norelgestromin
- Ethinyl Estradiol; Norethindrone
- Ethinyl Estradiol; Norethindrone Acetate
- Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
- Ethinyl Estradiol; Norethindrone; Ferrous fumarate
- Ethinyl Estradiol; Norgestimate
- Ethinyl Estradiol; Norgestrel
- Ethotoin
- Etomidate
- Etravirine
- Fedratinib
- Fenofibric Acid
- Fentanyl
- Fluconazole
- Flumazenil
- Fluoxetine
- Fluoxetine; Olanzapine
- Fluvoxamine
- food
- Fosphenytoin
- Fospropofol
- Gabapentin
- General anesthetics
- grapefruit juice
- Green Tea
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Guaifenesin; Phenylephrine
- Guanabenz
- Guanfacine
- Haloperidol
- Halothane
- Homatropine; Hydrocodone
- Hydrochlorothiazide, HCTZ; Methyldopa
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydromorphone
- Hydroxychloroquine
- Hydroxyzine
- Ibuprofen; Oxycodone
- Idelalisib
- Iloperidone
- Imatinib
- Isavuconazonium
- Isoflurane
- Isoniazid, INH
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Isoniazid, INH; Rifampin
- Itraconazole
- Ivacaftor
- Ketamine
- Ketoconazole
- Lasmiditan
- Letermovir
- Levocetirizine
- Levomethadyl
- Levomilnacipran
- Levorphanol
- Lisdexamfetamine
- Lithium
- Lofexidine
- Luliconazole
- Lumacaftor; Ivacaftor
- Lumacaftor; Ivacaftor
- Lumateperone
- Lurasidone
- Magnesium Hydroxide
- Magnesium Salts
- Maprotiline
- Meclizine
- Mefloquine
- Mepenzolate
- Meperidine
- Meperidine; Promethazine
- Mephobarbital
- Meprobamate
- Mestranol; Norethindrone
- Methadone
- Methocarbamol
- Methohexital
- Methscopolamine
- Methyldopa
- Metoclopramide
- Metyrapone
- Metyrosine
- Milnacipran
- Minocycline
- Mirtazapine
- Mitotane
- Mivacurium
- Modafinil
- Molindone
- Monoamine oxidase inhibitors
- Morphine
- Morphine; Naltrexone
- Nabilone
- Nalbuphine
- Nefazodone
- Neuromuscular blockers
- Nevirapine
- Nicardipine
- Nitroglycerin
- Olanzapine
- Ombitasvir; Paritaprevir; Ritonavir
- Ombitasvir; Paritaprevir; Ritonavir
- Omeprazole
- Omeprazole; Amoxicillin; Rifabutin
- Omeprazole; Sodium Bicarbonate
- Oritavancin
- Oxybutynin
- Oxycodone
- Oxymorphone
- Paliperidone
- Pancuronium
- Papaverine
- Pazopanib
- Pemoline
- Pentazocine
- Pentazocine; Naloxone
- Pentobarbital
- Perampanel
- Phenobarbital
- Phenothiazines
- Phentermine; Topiramate
- Phenylephrine
- Phenylephrine; Promethazine
- Phenytoin
- Pimozide
- Posaconazole
- Pramipexole
- Prasterone, Dehydroepiandrosterone, DHEA (Dietary Supplements)
- Prasterone, Dehydroepiandrosterone, DHEA (FDA-approved)
- Pregabalin
- Primidone
- Probenecid
- Procarbazine
- Propofol
- Propoxyphene
- Protease inhibitors
- Quetiapine
- Ramelteon
- Ranolazine
- Rapacuronium
- Rasagiline
- Remifentanil
- Ribociclib
- Ribociclib; Letrozole
- Rifabutin
- Rifampin
- Rifapentine
- Risperidone
- Rocuronium
- Ropinirole
- Rotigotine
- Rucaparib
- Safinamide
- Scopolamine
- Secobarbital
- Sedating H1-blockers
- Segesterone Acetate; Ethinyl Estradiol
- Sevoflurane
- Simeprevir
- Sincalide
- Skeletal Muscle Relaxants
- Sodium Bicarbonate
- Sodium Oxybate
- St. John’s Wort, Hypericum perforatum
- Streptogramins
- Succinylcholine
- Sufentanil
- Suvorexant
- Tacrine
- Tapentadol
- Teduglutide
- Telaprevir
- Telithromycin
- Telotristat Ethyl
- Tetrabenazine
- Tezacaftor; Ivacaftor
- Thalidomide
- Theophylline, Aminophylline
- Thiopental
- Thiothixene
- Tiagabine
- Tizanidine
- Topiramate
- Tramadol
- Trandolapril; Verapamil
- Trazodone
- Tricyclic antidepressants
- Trihexyphenidyl
- Trimethobenzamide
- Triprolidine
- Tubocurarine
- Valdecoxib
- Valerian, Valeriana officinalis
- Valproic Acid, Divalproex Sodium
- Vecuronium
- Vemurafenib
- Verapamil
- Vigabatrin
- Vilazodone
- Voriconazole
- Zafirlukast
- Zaleplon
- Zileuton
- Ziprasidone
- Zolpidem
