Cyclopentolate Phenylephrine Brand Name– Cyclomydril
What is Cyclopentolate Phenylephrine
Cyclopentolate and phenylephrine are used together in an ophthalmic preparation for producing mydriasis for ophthalmologic examination.
Cyclopentolate is a cycloplegic mydriatic agent that causes loss of accommodation and mydriasis.
Phenylephrine is a sympathomimetic agent that causes vasoconstriction and mydriasis.
The amount of mydriasis produced by this combination is greater than that produced by either agent alone.
Cyclomydril was approved by the FDA in September 1975
Indications
- mydriasis induction
For mydriasis induction for ophthalmic diagnostic procedures
Side Effects
- anhidrosis
- ataxia
- blurred vision
- dysarthria
- excitability
- fever
- hallucinations
- hypertension
- impaired cognition
- keratitis
- nasal dryness
- ocular irritation
- peripheral vasodilation
- photophobia
- psychosis
- restlessness
- seizures
- sinus tachycardia
- urinary retention
Monitoring Parameters
- ophthalmologic exam
Contraindications
- breast-feeding
- cardiac disease
- cerebral palsy
- children
- closed-angle glaucoma
- contact lenses
- Down’s syndrome
- driving or operating machinery
- geriatric
- head trauma
- hypertension
- hyperthyroidism
- increased intraocular pressure
- infants
- MAOI therapy
- neonates
- parenteral administration
- pregnancy
- premature neonates
- seizure disorder
- sunlight (UV) exposure
Interactions
There are no drug interactions associated with Cyclopentolate Phenylephrine products.
