Cyclopentolate Brand Names

AK-Pentolate | Cyclogyl | Cylate | Ocu-Pentolate

What is Cyclopentolate

Cyclopentolate is a cycloplegic, mydriatic ophthalmic agent with anticholinergic effects on the eye that are similar to atropine.

It is used for cycloplegic refraction and for dilating the pupil for diagnostic purposes.

This drug is useful as an aid to ophthalmic examination in a wide variety of populations, from newborns through the elderly.

Cyclopentolate was approved by the FDA in 1953.


  1. cycloplegia induction
  2. mydriasis induction

For mydriasis induction and cycloplegia induction for ophthalmic diagnostic procedures

Side Effects

  1. ataxia
  2. blurred vision
  3. conjunctivitis
  4. drowsiness
  5. dysarthria
  6. fever
  7. flushing
  8. hallucinations
  9. hyperemia
  10. hyperkinesis
  11. hypotension
  12. impaired cognition
  13. keratitis
  14. ocular hypertension
  15. ocular irritation
  16. ocular pain
  17. photophobia
  18. psychosis
  19. rash
  20. seizures
  21. sinus tachycardia
  22. urinary retention
  23. urticaria
  24. xerostomia

Monitoring Parameters

  • laboratory monitoring not necessary


  • breast-feeding
  • children
  • closed-angle glaucoma
  • contact lenses
  • Down’s syndrome
  • glaucoma
  • infants
  • pregnancy
  • seizure disorder
  • seizures


There are no drug interactions associated with Cyclopentolate products.


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