Ciprofloxacin Fluocinolone Brand Name– OTOVEL
What is Ciprofloxacin Fluocinolone
Ciprofloxacin fluocinolone otic solution is indicated for the treatment of acute otitis media due to susceptible organisms in pediatric patients aged 6 months and older with tympanostomy tubes.
Ciprofloxacin is a fluoroquinolone antibiotic with in vitro activity against a wide range of gram-positive and gram-negative microorganisms; topical use in the ear is not associated with ototoxicity.
Fluocinolone is an anti-inflammatory corticosteroid and is included to aid in the resolution of the inflammatory response associated with the bacterial infection.
Ciprofloxacin fluocinolone otic solution was FDA-approved in April 2016
Indications
- Haemophilus influenzae (beta-lactamase negative)
- Haemophilus influenzae (beta-lactamase positive)
- Moraxella catarrhalis
- otitis media
- Pseudomonas aeruginosa
- Staphylococcus aureus (MSSA)
- Streptococcus pneumoniae
Side Effects
- anaphylactoid reactions
- angioedema
- antimicrobial resistance
- candidiasis
- dizziness
- dysgeusia
- dyspnea
- edema
- flushing
- headache
- infection
- laryngeal edema
- otalgia
- paresthesias
- pruritus
- tinnitus
- urticaria
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- angioedema
- breast-feeding
- corticosteroid hypersensitivity
- ear discharge
- edema
- fungal infection
- herpes infection
- ophthalmic administration
- parenteral administration
- pregnancy
- quinolone hypersensitivity
- urticaria
- varicella
- viral infection
Interactions
There are no drug interactions associated with Ciprofloxacin Fluocinolone products.
