Ciprofloxacin Fluocinolone

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Ciprofloxacin Fluocinolone Brand Name– OTOVEL

What is Ciprofloxacin Fluocinolone

Ciprofloxacin fluocinolone otic solution is indicated for the treatment of acute otitis media due to susceptible organisms in pediatric patients aged 6 months and older with tympanostomy tubes.

Ciprofloxacin is a fluoroquinolone antibiotic with in vitro activity against a wide range of gram-positive and gram-negative microorganisms; topical use in the ear is not associated with ototoxicity.

Fluocinolone is an anti-inflammatory corticosteroid and is included to aid in the resolution of the inflammatory response associated with the bacterial infection.

Ciprofloxacin fluocinolone otic solution was FDA-approved in April 2016

Indications

  1. Haemophilus influenzae (beta-lactamase negative)
  2. Haemophilus influenzae (beta-lactamase positive)
  3. Moraxella catarrhalis
  4. otitis media
  5. Pseudomonas aeruginosa
  6. Staphylococcus aureus (MSSA)
  7. Streptococcus pneumoniae

Side Effects

  1. anaphylactoid reactions
  2. angioedema
  3. antimicrobial resistance
  4. candidiasis
  5. dizziness
  6. dysgeusia
  7. dyspnea
  8. edema
  9. flushing
  10. headache
  11. infection
  12. laryngeal edema
  13. otalgia
  14. paresthesias
  15. pruritus
  16. tinnitus
  17. urticaria

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • angioedema
  • breast-feeding
  • corticosteroid hypersensitivity
  • ear discharge
  • edema
  • fungal infection
  • herpes infection
  • ophthalmic administration
  • parenteral administration
  • pregnancy
  • quinolone hypersensitivity
  • urticaria
  • varicella
  • viral infection

Interactions

There are no drug interactions associated with Ciprofloxacin Fluocinolone products.

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