Aspirin Oxycodone

Aspirin Oxycodone Brand Names

Endodan | Percodan | Percodan-Demi

What is Aspirin Oxycodone

Aspirin oxycodone are used to treat moderate to severe pain due to cancer, dental procedures, headache, back pain, and arthralgias and myalgias.

Aspirin is an acetylated salicylate analgesic, which also has antiinflammatory, antipyretic, and antithrombotic effects.

Once in the body, it is hydrolyzed to salicylate, which is also active.

The antiinflammatory and analgesic effects of aspirin are roughly equivalent to those of many NSAIDs. Oxycodone is an opiate analgesic.

The combination of aspirin and oxycodone produces a greater analgesic effect than that produced by aspirin or oxycodone alone in the same doses. Combinations containing higher doses of one or both components give progressively increasing analgesia.

However, the maximum dose and ‘ceiling effect’ of aspirin limit the dosage escalation of this combination.

The combination of aspirin and opiate analgesics may achieve a ‘dose-sparing’ effect such that lower doses of the both agents produce pain relief with fewer side effects.

Aspirin oxycodone products are available in a tablet formulation.

Indications

1. arthralgia
2. bone pain
3. dental pain
4. headache
5. migraine
6. moderate pain
7. myalgia

Side Effects

1. abdominal pain
2. adrenocortical insufficiency
3. agitation
4. agranulocytosis
5. amenorrhea
6. anaphylactoid reactions
7. angioedema
8. anorexia
9. anxiety
10. aplastic anemia
11. apnea
12. asthenia
13. bleeding
14. bradycardia
15. bronchospasm
16. cardiac arrest
17. cerebral edema
18. coma
19. confusion
20. constipation
21. depression
22. diarrhea
23. dizziness
24. drowsiness
25. dyspepsia
26. dysphagia
27. dysphoria
28. dyspnea
29. ecchymosis
30. elevated hepatic enzymes
31. encephalopathy
32. eructation
33. erythema nodosum
34. esophageal stricture
35. esophageal ulceration
36. esophagitis
37. euphoria
38. fetal death
39. fever
40. flushing
41. GI bleeding
42. GI obstruction
43. GI perforation
44. gonadal suppression
45. hallucinations
46. headache
47. hearing loss
48. hemolytic anemia
49. hepatitis
50. hyperhidrosis
51. hyperuricemia
52. hypotension
53. hypothermia
54. hypoventilation
55. ileus
56. impotence (erectile dysfunction)
57. infertility
58. interstitial nephritis
59. laryngeal edema
60. lethargy
61. leukocytosis
62. leukopenia
63. libido decrease
64. maculopapular rash
65. malaise
66. miosis
67. nausea
68. neonatal opioid withdrawal syndrome
69. odynophagia
70. orthostatic hypotension
71. palpitations
72. pancreatitis
73. pancytopenia
74. paresthesias
75. peptic ulcer
76. physiological dependence
77. platelet dysfunction
78. postpartum hemorrhage
79. prolonged bleeding time
80. proteinuria
81. pruritus
82. psychological dependence
83. pulmonary edema
84. purpura
85. rash
86. renal failure (unspecified)
87. renal papillary necrosis
88. respiratory arrest
89. respiratory depression
90. restlessness
91. Reye’s syndrome
92. rhabdomyolysis
93. rhinitis
94. seizures
95. serotonin syndrome
96. Stevens-Johnson syndrome
97. syncope
98. tachypnea
99. thrombocytopenia
100. tinnitus
101. tolerance
102. toxic epidermal necrolysis
103. urinary retention
104. urticaria
105. visual impairment
106. vomiting
107. withdrawal
108. xerostomia

Monitoring Parameters

• LFTs
• serum creatinine/BUN

Contraindications

• abrupt discontinuation
• accidental exposure
• adrenal insufficiency
• anemia
• asthma
• bladder obstruction
• bone marrow suppression
• breast-feeding
• cardiac arrhythmias
• cardiac disease
• children
• chronic obstructive pulmonary disease (COPD)
• coadministration with other CNS depressants
• coagulopathy
• coma
• constipation
• cor pulmonale
• diarrhea
• driving or operating machinery
• G6PD deficiency
• geriatric
• GI disease
• GI obstruction
• head trauma
• hemophilia
• hepatic disease
• hypoprothrombinemia
• hypothyroidism
• hypovolemia
• hypoxemia
• ileus
• immunosuppression
• increased intracranial pressure
• infection
• infertility
• inflammatory bowel disease
• influenza
• intramuscular injections
• labor
• myxedema
• nasal polyps
• neonatal opioid withdrawal syndrome
• NSAID hypersensitivity
• obesity
• obstetric delivery
• oliguria
• opiate agonist hypersensitivity
• peptic ulcer disease
• potential for overdose or poisoning
• pregnancy
• prostatic hypertrophy
• pulmonary disease
• renal disease
• renal failure
• renal impairment
• reproductive risk
• respiratory depression
• respiratory insufficiency
• salicylate hypersensitivity
• scoliosis
• sleep apnea
• status asthmaticus
• substance abuse
• surgery
• systemic lupus erythematosus (SLE)
• thrombocytopenia
• ulcerative colitis
• urethral stricture
• urinary retention
• urticaria
• varicella
• viral infection
• vitamin K deficiency

Interactions

• Abciximab
• Acetaminophen
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Butalbital
• Acetaminophen; Butalbital; Caffeine
• Acetaminophen; Butalbital; Caffeine; Codeine
• Acetaminophen; Caffeine
• Acetaminophen; Caffeine; Dihydrocodeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
• Acetaminophen; Codeine
• Acetaminophen; Dextromethorphan
• Acetaminophen; Dextromethorphan; Doxylamine
• Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
• Acetaminophen; Dextromethorphan; Phenylephrine
• Acetaminophen; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Dichloralphenazone; Isometheptene
• Acetaminophen; Diphenhydramine
• Acetaminophen; Guaifenesin; Phenylephrine
• Acetaminophen; Hydrocodone
• Acetaminophen; Oxycodone
• Acetaminophen; Pentazocine
• Acetaminophen; Propoxyphene
• Acetaminophen; Pseudoephedrine
• Acetaminophen; Tramadol
• Acetazolamide
• Acetohexamide
• Acidifying Agents
• Acrivastine; Pseudoephedrine
• Ado-Trastuzumab emtansine
• Aldesleukin, IL-2
• Alfentanil
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Alkalinizing Agents
• Almotriptan
• Alogliptin
• Alogliptin; Metformin
• Alogliptin; Pioglitazone
• Alosetron
• Alpha-glucosidase Inhibitors
• Alprazolam
• Alvimopan
• Amide local anesthetics
• Amifampridine
• Amiloride
• Amiloride; Hydrochlorothiazide, HCTZ
• Aminoglycosides
• Amiodarone
• Amitriptyline
• Amitriptyline; Chlordiazepoxide
• Amlodipine
• Amlodipine; Atorvastatin
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Amoxapine
• Amoxicillin
• Amoxicillin; Clarithromycin; Lansoprazole
• Amoxicillin; Clarithromycin; Omeprazole
• Amoxicillin; Clavulanic Acid
• Amphotericin B
• Amphotericin B cholesteryl sulfate complex (ABCD)
• Amphotericin B lipid complex (ABLC)
• Amphotericin B liposomal (LAmB)
• Ampicillin
• Ampicillin; Sulbactam
• Anagrelide
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• Antithrombin III
• Antithymocyte Globulin
• Apalutamide
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• Aripiprazole
• Armodafinil
• Articaine; Epinephrine
• Ascorbic Acid, Vitamin C
• Asenapine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Atazanavir
• Atazanavir; Cobicistat
• Atenolol; Chlorthalidone
• Atomoxetine
• Atracurium
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Difenoxin
• Atropine; Diphenoxylate
• Azelastine
• Azelastine; Fluticasone
• Azilsartan; Chlorthalidone
• Bacitracin
• Baclofen
• Barbiturates
• Belladonna; Opium
• Benazepril
• Benazepril; Hydrochlorothiazide, HCTZ
• Bendroflumethiazide; Nadolol
• Benzhydrocodone; Acetaminophen
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Benzonatate
• Beta-blockers
• Bethanechol
• Betrixaban
• Bexarotene
• Bicalutamide
• Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
• Bismuth Subsalicylate
• Bismuth Subsalicylate; Metronidazole; Tetracycline
• Bisoprolol; Hydrochlorothiazide, HCTZ
• Bisphosphonates
• Boceprevir
• Bosentan
• Brexpiprazole
• Brigatinib
• Brimonidine
• Brimonidine; Brinzolamide
• Brimonidine; Timolol
• Bromocriptine
• Brompheniramine
• Brompheniramine; Carbetapentane; Phenylephrine
• Brompheniramine; Dextromethorphan; Guaifenesin
• Brompheniramine; Guaifenesin; Hydrocodone
• Brompheniramine; Hydrocodone; Pseudoephedrine
• Brompheniramine; Pseudoephedrine
• Bumetanide
• Bupivacaine
• Bupivacaine Liposomal
• Bupivacaine; Lidocaine
• Buprenorphine
• Buprenorphine; Naloxone
• Bupropion
• Bupropion; Naltrexone
• Buspirone
• Butorphanol
• Calcium Carbonate
• Calcium Carbonate; Magnesium Hydroxide
• Calcium Carbonate; Risedronate
• Calcium Carbonate; Simethicone
• Canagliflozin
• Canagliflozin; Metformin
• Candesartan; Hydrochlorothiazide, HCTZ
• Cannabidiol
• Capreomycin
• Capsaicin; Metaxalone
• Captopril
• Captopril; Hydrochlorothiazide, HCTZ
• Carbamazepine
• Carbenicillin
• Carbetapentane; Chlorpheniramine
• Carbetapentane; Chlorpheniramine; Phenylephrine
• Carbetapentane; Diphenhydramine; Phenylephrine
• Carbetapentane; Guaifenesin
• Carbetapentane; Guaifenesin; Phenylephrine
• Carbetapentane; Phenylephrine
• Carbetapentane; Phenylephrine; Pyrilamine
• Carbetapentane; Pseudoephedrine
• Carbetapentane; Pyrilamine
• Carbinoxamine
• Carbinoxamine; Dextromethorphan; Pseudoephedrine
• Carbinoxamine; Hydrocodone; Phenylephrine
• Carbinoxamine; Hydrocodone; Pseudoephedrine
• Carbinoxamine; Phenylephrine
• Carbinoxamine; Pseudoephedrine
• Cariprazine
• Carisoprodol
• Cefixime
• Cefotetan
• Celecoxib
• Cenobamate
• Ceritinib
• Cetirizine
• Cetirizine; Pseudoephedrine
• Chlophedianol; Dexbrompheniramine
• Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
• Chloral Hydrate
• Chloramphenicol
• Chlorcyclizine
• Chlordiazepoxide
• Chlordiazepoxide; Clidinium
• Chloroprocaine
• Chlorothiazide
• Chlorpheniramine
• Chlorpheniramine; Codeine
• Chlorpheniramine; Dextromethorphan
• Chlorpheniramine; Dextromethorphan; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
• Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Hydrocodone
• Chlorpheniramine; Hydrocodone; Phenylephrine
• Chlorpheniramine; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Phenylephrine
• Chlorpheniramine; Pseudoephedrine
• Chlorpromazine
• Chlorpropamide
• Chlorthalidone
• Chlorthalidone; Clonidine
• Chlorzoxazone
• Cidofovir
• Cilostazol
• Cimetidine
• Ciprofloxacin
• Cisatracurium
• Citalopram
• Citric Acid; Potassium Citrate
• Citric Acid; Potassium Citrate; Sodium Citrate
• Citric Acid; Sodium Citrate
• Clarithromycin
• Clemastine
• Clobazam
• Clomipramine
• Clonazepam
• Clonidine
• Clopidogrel
• Clorazepate
• Clozapine
• Cobicistat
• Codeine
• Codeine; Guaifenesin
• Codeine; Phenylephrine; Promethazine
• Codeine; Promethazine
• Colchicine; Probenecid
• Colistimethate, Colistin, Polymyxin E
• Collagenase
• COMT inhibitors
• Conivaptan
• Corticosteroids
• Crizotinib
• Crofelemer
• Cyclizine
• Cyclobenzaprine
• Cyclosporine
• Cyproheptadine
• Dabigatran
• Dabrafenib
• Dalfopristin; Quinupristin
• Dalteparin
• Danazol
• Dantrolene
• Dapagliflozin
• Dapagliflozin; Metformin
• Dapagliflozin; Saxagliptin
• Darifenacin
• Darunavir
• Darunavir; Cobicistat
• Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
• Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
• Deferasirox
• Defibrotide
• Delavirdine
• Desflurane
• Desipramine
• Desmopressin
• Deutetrabenazine
• Dexamethasone
• Dexchlorpheniramine
• Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
• Dexmedetomidine
• Dexpanthenol
• Dextromethorphan; Diphenhydramine; Phenylephrine
• Dextromethorphan; Promethazine
• Dextromethorphan; Quinidine
• Diazepam
• Dichlorphenamide
• Diclofenac
• Diclofenac; Misoprostol
• Dicloxacillin
• Diflunisal
• Dihydrocodeine; Guaifenesin; Pseudoephedrine
• Diltiazem
• Dimenhydrinate
• Diphenhydramine
• Diphenhydramine; Hydrocodone; Phenylephrine
• Diphenhydramine; Ibuprofen
• Diphenhydramine; Naproxen
• Diphenhydramine; Phenylephrine
• Dipyridamole
• Dolasetron
• Doravirine; Lamivudine; Tenofovir disoproxil fumarate
• Doxacurium
• Doxepin
• Doxylamine
• Doxylamine; Pyridoxine
• Dronabinol
• Dronedarone
• Droperidol
• Drotrecogin Alfa
• Duvelisib
• Edoxaban
• Efalizumab
• Efavirenz
• Efavirenz; Emtricitabine; Tenofovir
• Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
• Elagolix
• Elbasvir; Grazoprevir
• Eletriptan
• Elexacaftor; tezacaftor; ivacaftor
• Eliglustat
• Eltrombopag
• Eluxadoline
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
• Empagliflozin
• Empagliflozin; Linagliptin
• Empagliflozin; Linagliptin; Metformin
• Empagliflozin; Metformin
• Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
• Emtricitabine; Tenofovir disoproxil fumarate
• Enalapril, Enalaprilat
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Enflurane
• Enoxaparin
• Enzalutamide
• Epoprostenol
• Eprosartan; Hydrochlorothiazide, HCTZ
• Eptifibatide
• Ertugliflozin; Metformin
• Ertugliflozin; Sitagliptin
• Erythromycin
• Erythromycin; Sulfisoxazole
• Escitalopram
• Esketamine
• Eslicarbazepine
• Esomeprazole; Naproxen
• Estazolam
• Eszopiclone
• Ethacrynic Acid
• Ethanol
• Ethotoin
• Etodolac
• Etomidate
• Etravirine
• Everolimus
• Famotidine; Ibuprofen
• Fedratinib
• Fenoprofen
• Fentanyl
• Fesoterodine
• Fish Oil, Omega-3 Fatty Acids (Dietary Supplements)
• Flavocoxid, Flavocoxid; Citrated Zinc Bisglycinate
• Flibanserin
• Fluconazole
• Fluoxetine
• Fluoxetine; Olanzapine
• Fluphenazine
• Flurazepam
• Flurbiprofen
• Fluvoxamine
• Fondaparinux
• Fosamprenavir
• Foscarnet
• Fosinopril
• Fosinopril; Hydrochlorothiazide, HCTZ
• Fosphenytoin
• Fospropofol
• Fostamatinib
• Frovatriptan
• Furosemide
• Gabapentin
• Gallium Ga 68 Dotatate
• Garlic, Allium sativum
• Gefitinib
• General anesthetics
• Ginger, Zingiber officinale
• Ginkgo, Ginkgo biloba
• Glimepiride
• Glimepiride; Pioglitazone
• Glimepiride; Rosiglitazone
• Glipizide
• Glipizide; Metformin
• Glyburide
• Glyburide; Metformin
• Granisetron
• grapefruit juice
• Green Tea
• Griseofulvin
• Guaifenesin; Hydrocodone
• Guaifenesin; Hydrocodone; Pseudoephedrine
• Guanabenz
• Guanfacine
• Haloperidol
• Halothane
• Heparin
• Homatropine; Hydrocodone
• Hyaluronidase
• Hyaluronidase, Recombinant; Immune Globulin
• Hydralazine; Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Methyldopa
• Hydrochlorothiazide, HCTZ; Metoprolol
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone
• Hydrocodone; Ibuprofen
• Hydrocodone; Phenylephrine
• Hydrocodone; Potassium Guaiacolsulfonate
• Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
• Hydrocodone; Pseudoephedrine
• Hydromorphone
• Hydroxyzine
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Ibritumomab Tiuxetan
• Ibrutinib
• Ibuprofen
• Ibuprofen; Oxycodone
• Ibuprofen; Pseudoephedrine
• Idelalisib
• Iloperidone
• Iloprost
• Imatinib
• Imipramine
• Immune Globulin IV, IVIG, IGIV
• Incretin Mimetics
• Indapamide
• Indinavir
• Indomethacin
• Inotersen
• Insulins
• Intravenous Lipid Emulsions
• Iron Sucrose, Sucroferric Oxyhydroxide
• Isavuconazonium
• Isoflurane
• Isoniazid, INH
• Isoniazid, INH; Pyrazinamide, PZA; Rifampin
• Isoniazid, INH; Rifampin
• Istradefylline
• Itraconazole
• Ivacaftor
• Ketamine
• Ketoconazole
• Ketoprofen
• Ketorolac
• Lamivudine; Tenofovir Disoproxil Fumarate
• Lansoprazole; Naproxen
• Lapatinib
• Larotrectinib
• Lasmiditan
• Lefamulin
• Lemborexant
• Lesinurad
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• Levocetirizine
• Levorphanol
• Lidocaine
• Linagliptin
• Linagliptin; Metformin
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• Loperamide; Simethicone
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• Meperidine; Promethazine
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• Rituximab; Hyaluronidase
• Rivaroxaban
• Rizatriptan
• Rocuronium
• Rolapitant
• Ropinirole
• Ropivacaine
• Rosiglitazone
• Rotigotine
• Rucaparib
• Salicylic Acid
• Saquinavir
• Saxagliptin
• Selective norepinephrine reuptake inhibitors
• Selective serotonin reuptake inhibitors
• Serotonin norepinephrine reuptake inhibitors
• Serotonin-Receptor Agonists
• Serotonin-Receptor Antagonists
• Sertraline
• Sevoflurane
• Sibutramine
• Sildenafil
• Simeprevir
• Simvastatin; Sitagliptin
• Sitagliptin
• Skeletal Muscle Relaxants
• Sodium Bicarbonate
• Sodium Hyaluronate, Hyaluronic Acid
• Sodium Lactate
• Sodium Oxybate
• Sodium Thiosulfate; Salicylic Acid
• Solifenacin
• Spironolactone
• St. John’s Wort, Hypericum perforatum
• Streptogramins
• Succinylcholine
• Sulfinpyrazone
• Sulfonamides
• Sulfonylureas
• Sulindac
• Sumatriptan
• Suvorexant
• Tacrolimus
• Tapentadol
• Tasimelteon
• Telaprevir
• Telavancin
• Telithromycin
• Telotristat Ethyl
• Temazepam
• Tenofovir Alafenamide
• Tenofovir, PMPA
• Terbinafine
• Tetrabenazine
• Tetracaine
• Tezacaftor; Ivacaftor
• Thalidomide
• Thiazide diuretics
• Thiazolidinediones
• Thiethylperazine
• Thioridazine
• Thiothixene
• Thrombin Inhibitors
• Thrombolytic Agents
• Ticagrelor
• Ticarcillin
• Ticarcillin; Clavulanic Acid
• Ticlopidine
• Tinzaparin
• Tipranavir
• Tirofiban
• Tizanidine
• Tolazamide
• Tolbutamide
• Tolmetin
• Tolterodine
• Topiramate
• Torsemide
• Tramadol
• Trandolapril
• Trandolapril; Verapamil
• Trastuzumab; Hyaluronidase
• Trazodone
• Treprostinil
• Triamterene
• Triazolam
• Tricyclic antidepressants
• Trifluoperazine
• Trimethobenzamide
• Trimipramine
• Triprolidine
• Tromethamine
• Trospium
• Tubocurarine
• Valerian, Valeriana officinalis
• Valproic Acid, Divalproex Sodium
• Vancomycin
• Varicella-Zoster Virus Vaccine, Live
• Vecuronium
• Vemurafenib
• Verapamil
• Verteporfin
• Vigabatrin
• Vilazodone
• Vorapaxar
• Voriconazole
• Vortioxetine
• Voxelotor
• Warfarin
• Zafirlukast
• Zaleplon
• Ziconotide
• Ziprasidone
• Zolmitriptan
• Zolpidem