Albumin

Albumin Brand Names

Albuked | Albumarc | Albuminar | Albuminex | AlbuRx | Albutein | Buminate | Flexbumin | Kedbumin | Macrotec | Plasbumin

What is Albumin

Albumin is a parenteral colloid indicated for hypovolemia, hypoalbuminemia, prevention of central volume depletion after paracentesis due to cirrhotic ascites, ovarian hyperstimulation syndrome, adult respiratory distress syndrome, acute nephrosis, hemolytic disease of the newborn, burns, cardiopulmonary bypass surgery, and erythrocyte resuspension during exchange transfusion to prevent hypoproteinemia.

The main clinical indications are for hypoproteinemic states involving reduced oncotic pressure, with or without edema.

Albumin is made from large pools of human venous plasma by the Cohn cold ethanol fractionation process.

As with other products derived from or purified with human blood components, the remote possibility of contamination with Creutzfeldt-Jakob disease (CJD) or other viral infections exists in patients receiving albumin. The manufacturing processes are designed to reduce the risk of transmitting viral infection.

No cases of transmission of viral illness or CJD have ever been identified for albumin

Indications

1. acute respiratory distress syndrome (ARDS)
2. burns
3. cardiopulmonary bypass
4. erythroblastosis fetalis
5. hepatic cirrhosis
6. hyperbilirubinemia
7. hypoproteinemia
8. hypovolemia
9. nephrotic syndrome

For the treatment of shock due to hypovolemia

Side Effects

1. abdominal pain
2. aluminum toxicity
3. anaphylactic shock
4. anaphylactoid reactions
5. angioedema
6. atrial fibrillation
7. bradycardia
8. bronchospasm
9. chills
10. confusion
11. dyspnea
12. edema
13. fever
14. flushing
15. headache
16. heart failure
17. hyperhidrosis
18. hypersalivation
19. hypertension
20. hypervolemia
21. hypotension
22. infection
23. loss of consciousness
24. myocardial infarction
25. nausea
26. pruritus
27. pulmonary edema
28. rash
29. sinus tachycardia
30. urticaria
31. vomiting

Monitoring Parameters

• blood pressure
• hemoglobin/hematocrit
• serum albumin
• serum electrolytes

Contraindications

• albumin hypersensitivity
• anemia
• breast-feeding
• coagulopathy
• dehydration
• electrolyte imbalance
• esophageal varices
• heart failure
• hypertension
• pregnancy
• premature neonates
• pulmonary edema
• renal disease
• renal failure
• surgery
• trauma
• viral infection

Interactions

There are no drug interactions associated with Albumin products.