Acetaminophen Dextromethorphan Pseudoephedrine

Acetaminophen Dextromethorphan Pseudoephedrine Brand Names

666 Cold | Alka-Seltzer Plus Cold | Contac Cold and Flu | Day-Time Cold/Flu Relief | Sudafed Severe Cold | Triaminic Cough and Sore Throat | Triaminic Cough and Sore Throat Softchew | Tylenol Cold and Flu Severe Daytime | Tylenol Cold Daytime | Tylenol Flu | Tylenol Infants’ Cold and Cough | Vicks DayQuil

What is Acetaminophen Dextromethorphan Pseudoephedrine

Acetaminophen Dextromethorphan Pseudoephedrine are used together to provide temporary relief from common cold or flu symptoms such as mild pain, cough, nasal congestion, headache, sore throat, and fever.

Indications

1. common cold
2. cough
3. fever
4. headache
5. mild pain
6. nasal congestion
7. pharyngitis

Side Effects

1. abdominal pain
2. acute generalized exanthematous pustulosis (AGEP)
3. agranulocytosis
4. anaphylactic shock
5. anaphylactoid reactions
6. angina
7. angioedema
8. anorexia
9. anxiety
10. arrhythmia exacerbation
11. bleeding
12. bradycardia
13. colitis
14. confusion
15. contact dermatitis
16. dizziness
17. drowsiness
18. dysarthria
19. dysuria
20. elevated hepatic enzymes
21. encephalopathy
22. erythema
23. excitability
24. exfoliative dermatitis
25. fever
26. GI bleeding
27. hallucinations
28. headache
29. hemolysis
30. hemolytic anemia
31. hepatic necrosis
32. hypertension
33. hypoprothrombinemia
34. insomnia
35. interstitial nephritis
36. irritability
37. jaundice
38. maculopapular rash
39. methemoglobinemia
40. myocardial infarction
41. myocarditis
42. nausea
43. ocular hypertension
44. pancytopenia
45. pruritus
46. psychosis
47. purpura
48. rash
49. renal failure (unspecified)
50. renal papillary necrosis
51. renal tubular necrosis
52. restlessness
53. stroke
54. thrombocytopenia
55. thrombocytosis
56. toxic epidermal necrolysis
57. urinary retention
58. urticaria
59. vomiting
60. xerostomia

Monitoring Parameters

• laboratory monitoring not necessary

Contraindications

• acute myocardial infarction
• alcoholism
• aneurysm
• angina
• arteriosclerosis
• asthma
• atrial fibrillation
• atrial flutter
• AV block
• bladder obstruction
• bone marrow suppression
• bradycardia
• breast-feeding
• bronchitis
• bundle-branch block
• cardiac arrhythmias
• cardiac disease
• cardiomyopathy
• cerebrovascular disease
• children
• chronic obstructive pulmonary disease (COPD)
• closed-angle glaucoma
• coronary artery disease
• diabetes mellitus
• driving or operating machinery
• emphysema
• G6PD deficiency
• geriatric
• heart failure
• hepatic disease
• hepatitis
• hypertension
• hyperthyroidism
• immunosuppression
• increased intraocular pressure
• infants
• infection
• intracranial bleeding
• labor
• MAOI therapy
• myocardial infarction
• neonates
• obstetric delivery
• organic brain syndrome
• peripheral vascular disease
• pregnancy
• prostatic hypertrophy
• renal disease
• renal failure
• renal impairment
• stroke
• tachycardia
• thyrotoxicosis
• tobacco smoking
• urinary retention
• ventricular fibrillation
• ventricular tachycardia

Interactions

• Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
• Abiraterone
• Acarbose
• Acebutolol
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Butalbital
• Acetaminophen; Butalbital; Caffeine
• Acetaminophen; Butalbital; Caffeine; Codeine
• Acetaminophen; Caffeine
• Acetaminophen; Caffeine; Dihydrocodeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
• Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
• Acetaminophen; Codeine
• Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
• Acetaminophen; Dextromethorphan; Phenylephrine
• Acetaminophen; Guaifenesin; Phenylephrine
• Acetazolamide
• Aclidinium; Formoterol
• Albiglutide
• Albuterol
• Albuterol; Ipratropium
• Alfentanil
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Alkalinizing Agents
• Alogliptin; Metformin
• Alogliptin; Pioglitazone
• Alpha-blockers
• Alpha-glucosidase Inhibitors
• Aluminum Hydroxide
• Aluminum Hydroxide; Magnesium Carbonate
• Aluminum Hydroxide; Magnesium Hydroxide
• Aluminum Hydroxide; Magnesium Hydroxide; Simethicone
• Aluminum Hydroxide; Magnesium Trisilicate
• Amiloride; Hydrochlorothiazide, HCTZ
• Amiodarone
• Amlodipine
• Amlodipine; Atorvastatin
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Ammonium Chloride
• Amobarbital
• Amoxapine
• Angiotensin II receptor antagonists
• Angiotensin-converting enzyme inhibitors
• Antacids
• Aprepitant, Fosaprepitant
• Arformoterol
• Artemether; Lumefantrine
• Articaine; Epinephrine
• Aspirin, ASA
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Aspirin, ASA; Omeprazole
• Aspirin, ASA; Oxycodone
• Aspirin, ASA; Pravastatin
• Atazanavir; Cobicistat
• Atenolol
• Atenolol; Chlorthalidone
• Atomoxetine
• Atropine
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Difenoxin
• Atropine; Diphenoxylate
• Atropine; Edrophonium
• Atropine; Hyoscyamine; Phenobarbital; Scopolamine
• Azilsartan; Chlorthalidone
• Barbiturates
• Belladonna Alkaloids; Ergotamine; Phenobarbital
• Benazepril
• Benazepril; Hydrochlorothiazide, HCTZ
• Bendroflumethiazide; Nadolol
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Beta-blockers
• Betaxolol
• Bethanechol
• Bismuth Subsalicylate
• Bismuth Subsalicylate; Metronidazole; Tetracycline
• Bisoprolol
• Bisoprolol; Hydrochlorothiazide, HCTZ
• Boceprevir
• Bosentan
• Bretylium
• Brimonidine; Timolol
• Bromocriptine
• Brompheniramine; Carbetapentane; Phenylephrine
• Budesonide; Formoterol
• Bumetanide
• Bupivacaine
• Bupivacaine Liposomal
• Bupivacaine; Lidocaine
• Buprenorphine
• Buprenorphine; Naloxone
• Bupropion
• Bupropion; Naltrexone
• Busulfan
• Butabarbital
• Caffeine
• Caffeine; Ergotamine
• Calcium Carbonate
• Calcium Carbonate; Magnesium Hydroxide
• Calcium Carbonate; Risedronate
• Calcium Carbonate; Simethicone
• Calcium-channel blockers
• Canagliflozin
• Canagliflozin; Metformin
• Candesartan; Hydrochlorothiazide, HCTZ
• Captopril
• Captopril; Hydrochlorothiazide, HCTZ
• Carbamazepine
• Carbetapentane; Chlorpheniramine; Phenylephrine
• Carbetapentane; Diphenhydramine; Phenylephrine
• Carbetapentane; Guaifenesin; Phenylephrine
• Carbetapentane; Phenylephrine
• Carbetapentane; Phenylephrine; Pyrilamine
• Carbinoxamine; Hydrocodone; Phenylephrine
• Carbinoxamine; Phenylephrine
• Cardiac glycosides
• Carteolol
• Carvedilol
• Celecoxib
• Charcoal
• Chlophedianol; Guaifenesin; Phenylephrine
• Chloroprocaine
• Chlorothiazide
• Chlorpheniramine; Codeine
• Chlorpheniramine; Dextromethorphan; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Phenylephrine
• Chlorpheniramine; Hydrocodone; Phenylephrine
• Chlorpheniramine; Phenylephrine
• Chlorthalidone
• Chlorthalidone; Clonidine
• Cholestyramine
• Choline Salicylate; Magnesium Salicylate
• Cinacalcet
• Citalopram
• Clevidipine
• Clobazam
• Clonidine
• Cobicistat
• Cocaine
• Codeine
• Codeine; Guaifenesin
• Codeine; Phenylephrine; Promethazine
• Codeine; Promethazine
• Colchicine
• Colchicine; Probenecid
• Dacomitinib
• Dapagliflozin
• Dapagliflozin; Metformin
• Dapagliflozin; Saxagliptin
• Dapsone
• Darifenacin
• Darunavir; Cobicistat
• Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
• Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
• Delavirdine
• Desvenlafaxine
• Dextromethorphan; Diphenhydramine; Phenylephrine
• Dextromethorphan; Guaifenesin; Phenylephrine
• Diflunisal
• Digitoxin
• Digoxin
• Dihydroergotamine
• Diltiazem
• Dipeptidyl Peptidase-4 Inhibitors
• Diphenhydramine; Hydrocodone; Phenylephrine
• Diphenhydramine; Phenylephrine
• Donepezil; Memantine
• Dopamine
• Dorzolamide; Timolol
• Dronabinol
• Dronedarone
• Drospirenone; Ethinyl Estradiol
• Drospirenone; Ethinyl Estradiol; Levomefolate
• Droxidopa
• Dulaglutide
• Duloxetine
• Dyphylline
• Dyphylline; Guaifenesin
• Efavirenz
• Efavirenz; Emtricitabine; Tenofovir
• Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
• Eliglustat
• Eltrombopag
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
• Empagliflozin
• Empagliflozin; Linagliptin
• Empagliflozin; Linagliptin; Metformin
• Empagliflozin; Metformin
• Enalapril, Enalaprilat
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Ephedrine
• Epoprostenol
• Eprosartan; Hydrochlorothiazide, HCTZ
• Ergoloid Mesylates
• Ergonovine
• Ergot alkaloids
• Ergotamine
• Ertugliflozin
• Ertugliflozin; Metformin
• Ertugliflozin; Sitagliptin
• Escitalopram
• Esmolol
• Ethacrynic Acid
• Ethanol
• Ethinyl Estradiol
• Ethinyl Estradiol; Desogestrel
• Ethinyl Estradiol; Ethynodiol Diacetate
• Ethinyl Estradiol; Etonogestrel
• Ethinyl Estradiol; Levonorgestrel
• Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
• Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
• Ethinyl Estradiol; Norelgestromin
• Ethinyl Estradiol; Norethindrone
• Ethinyl Estradiol; Norethindrone Acetate
• Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
• Ethinyl Estradiol; Norethindrone; Ferrous fumarate
• Ethinyl Estradiol; Norgestimate
• Ethinyl Estradiol; Norgestrel
• Exenatide
• Fedratinib
• Felodipine
• Fentanyl
• Fluoxetine
• Fluoxetine; Olanzapine
• Fluticasone; Salmeterol
• Fluticasone; Umeclidinium; Vilanterol
• Fluticasone; Vilanterol
• Fluvoxamine
• Formoterol
• Formoterol; Mometasone
• Fosinopril
• Fosinopril; Hydrochlorothiazide, HCTZ
• Furosemide
• Ginger, Zingiber officinale
• Givosiran
• Glimepiride; Pioglitazone
• Glimepiride; Rosiglitazone
• Glipizide; Metformin
• Glyburide; Metformin
• Glycopyrrolate; Formoterol
• grapefruit juice
• Green Tea
• Guaifenesin; Phenylephrine
• Guanabenz
• Halogenated Anesthetics
• Haloperidol
• Hydantoins
• Hydralazine; Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Methyldopa
• Hydrochlorothiazide, HCTZ; Metoprolol
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone; Phenylephrine
• Hydroxyprogesterone
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Iloprost
• Imatinib
• Incretin Mimetics
• Indacaterol
• Indacaterol; Glycopyrrolate
• Indapamide
• Insulin Degludec; Liraglutide
• Insulin Glargine; Lixisenatide
• Insulins
• Iobenguane I 131
• Isavuconazonium
• Isocarboxazid
• Isoniazid, INH
• Isoniazid, INH; Pyrazinamide, PZA; Rifampin
• Isoniazid, INH; Rifampin
• Isradipine
• Labetalol
• Lamivudine, 3TC; Zidovudine, ZDV
• Lamotrigine
• Lanthanum Carbonate
• Lasmiditan
• Levalbuterol
• Levobetaxolol
• Levobunolol
• Levomilnacipran
• Levothyroxine
• Levothyroxine; Liothyronine (Porcine)
• Levothyroxine; Liothyronine (Synthetic)
• Lidocaine
• Lidocaine; Prilocaine
• Linagliptin; Metformin
• Linezolid
• Liothyronine
• Liraglutide
• Lisinopril
• Lixisenatide
• Lomitapide
• Loop diuretics
• Lopinavir; Ritonavir
• Lorcaserin
• Macitentan
• Magnesium Salicylate
• Maprotiline
• Mecamylamine
• Meglitinides
• Memantine
• Mephobarbital
• Mepivacaine
• Mepivacaine; Levonordefrin
• Metaproterenol
• Metformin
• Metformin; Pioglitazone
• Metformin; Repaglinide
• Metformin; Rosiglitazone
• Metformin; Saxagliptin
• Metformin; Sitagliptin
• Methazolamide
• Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
• Methohexital
• Methyclothiazide
• Methyldopa
• Methylene Blue
• Methylergonovine
• Methysergide
• Metolazone
• Metoprolol
• Metyrapone
• Midodrine
• Miglitol
• Milnacipran
• Mipomersen
• Mirabegron
• Mirtazapine
• Mitotane
• Moexipril
• Monoamine oxidase inhibitors
• Nabilone
• Nadolol
• Nebivolol
• Nebivolol; Valsartan
• Nefazodone
• Nicardipine
• Nicotine
• Nifedipine
• Nimodipine
• Nisoldipine
• Nitrates
• Norepinephrine
• Ombitasvir; Paritaprevir; Ritonavir
• Omeprazole; Amoxicillin; Rifabutin
• Omeprazole; Sodium Bicarbonate
• Oritavancin
• Ozanimod
• Panobinostat
• Paroxetine
• Pazopanib
• Peginterferon Alfa-2b
• Penbutolol
• Penicillin G Benzathine; Penicillin G Procaine
• Penicillin G Procaine
• Pentobarbital
• Pergolide
• Perindopril
• Perindopril; Amlodipine
• Phenelzine
• Phenobarbital
• Phenylephrine
• Phenylephrine; Promethazine
• Pindolol
• Pioglitazone
• Pirbuterol
• Pneumococcal Vaccine, Polyvalent
• Posaconazole
• Potassium-sparing diuretics
• Pramlintide
• Prilocaine
• Prilocaine; Epinephrine
• Primidone
• Procarbazine
• Propafenone
• Propranolol
• Quinapril
• Quinine
• Racepinephrine
• Ramipril
• Rasagiline
• Reserpine
• Rifabutin
• Rifampin
• Riociguat
• Ritonavir
• Rolapitant
• Ropivacaine
• Rosiglitazone
• Safinamide
• Salmeterol
• Salsalate
• Secobarbital
• Segesterone Acetate; Ethinyl Estradiol
• Selegiline
• Selexipag
• Semaglutide
• Serotonin-Receptor Agonists
• Sertraline
• SGLT2 Inhibitors
• Sibutramine
• Sodium Bicarbonate
• Solriamfetol
• Sotalol
• St. John’s Wort, Hypericum perforatum
• Sulfinpyrazone
• Sulfonylureas
• Tedizolid
• Telaprevir
• Telotristat Ethyl
• Terbinafine
• Terbutaline
• Tetracaine
• Theophylline, Aminophylline
• Thiazide diuretics
• Thiazolidinediones
• Thiopental
• Thyroid hormones
• Timolol
• Tizanidine
• tobacco
• Tocilizumab
• Torsemide
• Trandolapril
• Trandolapril; Verapamil
• Tranylcypromine
• Treprostinil
• Tricyclic antidepressants
• Trimetrexate
• Umeclidinium; Vilanterol
• Vasodilators
• Vasopressors
• Vemurafenib
• Venlafaxine
• Verapamil
• Vilazodone
• Vortioxetine
• Warfarin
• Yohimbine
• Zidovudine, ZDV
• Zolmitriptan