What is Saw Palmetto (Serenoa repens) Saw palmetto is derived from the partially dried, ripe fruit of Serenoa repens, a palm plant of the family Arecaceae that grows from South Carolina to Florida. The medicinal use of this herb has been documented since the 1800’s. Native Americans used the berries to treat testicular atrophy, infertility, and …
What is Saxagliptin Saxagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor and is used in the treatment of type 2 diabetes mellitus (DM) in adults. DPP-4 inhibitors potentiate the effects of the incretin hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP), by inhibiting their breakdown by DPP-4. Among treatment-naive adults receiving saxagliptin with a …
What is Sarilumab Sarilumab is an injectable interleukin-6 (IL-6) receptor antagonist. In patients with inflammatory diseases such as rheumatoid arthritis, IL-6 concentrations correlate with disease activity and joint or tissue damage. Sarilumab is used for the treatment of adults with moderate to severe rheumatoid arthritis who have had an inadequate response or intolerance to one …
What is Sargramostim (GM CSF) Sargramostim is a recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF). It works by promoting proliferation and differentiation of hematopoietic progenitor cells. Sargramostim is used as primary prophylaxis following induction therapy in older patients with acute myelogenous leukemia; for peripheral blood stem cell (PBSC) mobilization for collection by leukapheresis; following an autologous …
What is Sarecycline Sarecycline is a tetracycline-class antibiotic indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 9 years of age and older. The efficacy of sarecycline was established in 2 clinical trials in patients with acne. At 12 weeks, a significantly higher proportion of sarecycline-treated patients had …
What is Saquinavir Saquinavir is an antiretroviral protease inhibitor, indicated for use in combination with ritonavir and other antiretroviral medications to treat HIV-1 infection in patients 16 years and older. To obtain adequate plasma concentrations, saquinavir MUST always be ‘boosted’ with ritonavir; cobicistat is NOT interchangeable with ritonavir to increase the exposure of saquinavir. Dose-dependent …
What is Sapropterin Sapropterin is indicated in conjunction with a phenylalanine-restricted diet to reduce blood phenylalanine concentrations in patients with hyperphenylalaninemia due to tetrahydrobiopterin- (BH4-) responsive phenylketonuria (PKU). Sapropterin is a synthetic form, 6R-BH4, of tetrahydrobiopterin and was the first FDA-approved drug to treat PKU. Brand Name KUVAN Indications phenylketonuria (PKU) Side Effects abdominal pain …