What is Selpercatinib Selpercatinib is a kinase inhibitor that targets wild-type RET and multiple mutated RET isoforms. It is indicated for the treatment of adult patients with metastatic RET fusion-positive non-small cell lung cancer (NSCLC), adult and pediatric patients 12 years of age and older with advanced or metastatic RET-mutant medullary thyroid cancer who require …
What is Selinexor Selinexor is a nuclear export inhibitor. It is indicated in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least 4 prior therapies and have refractory disease to at least 2 proteasome inhibitors, at least 2 immunomodulatory agents, and an anti-CD38 monoclonal …
What is Selexipag Selexipag is an oral, selective prostacyclin receptor (IP receptor) agonist for the treatment of pulmonary arterial hypertension (PAH, WHO Group I) to delay disease progression and reduce the risk of hospitalization for PAH. Current pharmacologic options for the treatment of PAH are targeted to specific pathways involved in the disease process; many …
What is Selenium Sulfide Selenium sulfide is a topical antiseborrheic and antifungal product. It is labeled for treatment of dandruff, seborrheic dermatitis of the scalp, and tinea versicolor. It has also been used in the treatment of psoriasis and as an adjunct to oral antifungals for tinea capitis therapy. Selenium sulfide is available in a …
What is Selenium Selenium is an essential nonmetallic element which is chemically related to sulfur. It is found in rock, shale, sandstone, limestone, coal, soil, surface water, and vegetation. Foods which contain significant amounts of selenium include meat, poultry, grains, and seafood. Selenium concentrations are relatively high in many of the soils of the United …
What is Selegiline Selegiline is classified as a selective monoamine oxidase (MAO) type-B inhibitor. Selegiline is available orally for the treatment of Parkinson’s disease as an adjunct to levodopa/carbidopa, and transdermally for the treatment of major depressive disorder. Brand Name Carbex Eldepryl EMSAM Zelapar Indications depression Parkinson’s disease parkinsonism Side Effects abdominal pain agitation akinesia …
What is Segesterone Acetate and Ethinyl Estradiol Segesterone acetate and ethinyl estradiol and used together in a combination hormonal contraceptive vaginal system (ring). Ethinyl estradiol is a potent, synthetic estrogen. Segesterone, also known as 17alpha-hydroxy-16-methylene-19-norprogesterone or as 17alpha-deacetylnestorone, is a synthetic progestin. Segesterone has high progestational activity with negligible androgenic, glucocorticoid, or estrogenic activity in …