What is Sirolimus Sirolimus (rapamycin) is an immunosuppressant. Sirolimus is a macrolide produced by Streptomyces hydroscopicus, a streptomycete that was isolated from a soil sample from Easter Island. Sirolimus has antifungal, antitumor, and immunosuppressive activities. Brand Name Rapamune Indications & Dosage heart transplant rejection prophylaxis kidney transplant rejection prophylaxis lymphangioleiomyomatosis For kidney transplant rejection prophylaxis Side …
What is Sipuleucel-T Sipuleucel-T (Provenge or APC-8015) is an autologous cellular immunotherapy used for the treatment of prostate cancer. Brand Name Provenge Indications & Dosage prostate cancer For the treatment of asymptomatic or minimally symptomatic metastatic, castrate resistant (hormone refractory), prostate cancer NOTE: Approximately 3 days prior to each infusion of sipuleucel-T, a standard leukapheresis …
What is Siponimod Siponimod is an oral sphingosine 1-phosphate receptor modulator indicated for the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. Brand Name MAYZENT Indications & Dosage multiple sclerosis Side Effects asthenia AV block bradycardia diarrhea dizziness dyspnea elevated hepatic enzymes encephalopathy …
What is Sinecatechins Sinecatechins 15% ointment is a topical agent for the treatment of external genital and perianal warts (i.e. condylomata acuminata). Sinecatechins ointment is a botanical drug product made from green tea leaves (Camellia sinensis (L.) O Kuntze) extract. Green tea catechins constitute 85—95% of the drug substance, with more than 55% being epigallocatechin …
What is Sincalide Sincalide is a synthetically prepared cholecystopancreatic-gastrointestinal hormone peptide for parenteral administration. Structurally, it is an eight chain peptide of the C-terminal of cholecystokinin. Activities include gallbladder contraction, sphincter of Oddi relaxation, hepatic bile secretion, pancreatic secretion stimulation, and intestinal smooth muscle stimulation. Sincalide has been studied in the treatment and prevention of …
What is Simvastatin and Sitagliptin combination medicine Simvastatin; sitagliptin (Juvisync) is FDA-approved for treating patients in whom treatment with both simvastatin and sitagliptin is appropriate. Simvastatin is an HMG-CoA reductase inhibitor indicated as adjunctive therapy to diet to reduce the risk of total mortality by reducing CHD deaths and reduce the risk of non-fatal myocardial …
What is Simvastatin Simvastatin is an oral antilipemic agent which inhibits HMG-CoA reductase. Simvastatin is the methylated form of lovastatin. Both simvastatin and lovastatin are prodrugs that require hydrolysis for activation. Simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein …