What is Sorbitol Sorbitol (chemical designation D-glucitol) is a sugar alcohol found naturally in fruits. It is used as a low-calorie sweetener in some sugarless candies and gum and has been studied in the prevention of dental caries. Similar to some other sugar alcohols, the FDA has approved the label ‘does not promote tooth decay’ for sugar-free …
What is Sorafenib Sorafenib is a multi-kinase inhibitor targeting several intracellular and cell surface kinases, including c-CRAF, BRAF, mutant BRAF, vascular endothelial growth factor (VEGF) receptors -1, -2 and -3, platelet-derived growth factor receptor-beta (PDGFR-beta), KIT, FLT-3, and RET. It is indicated as monotherapy for the treatment of unresectable hepatocellular carcinoma, advanced renal cell carcinoma, …
What is Sonidegib Sonidegib (LDE225) is an oral inhibitor of smoothened (SMO), a transmembrane protein involved in Hedgehog (Hh) signal transduction, which is important in normal embryogenic growth and development, and becomes less active in adults. SMO is normally inhibited by another transmembrane protein, patched (PTCH1). Abnormal Hh signaling plays an important role in basal …
What is Somatropin rh GH Somatropin, rh-GH is a purified recombinant growth hormone prepared by using either Escherichia coli or mammalian-cells. Endogenous human growth hormone (hGH) is produced in the pituitary gland. Growth hormone was first isolated in 1956, and its structure was identified in 1972. Prior to 1985, growth hormone (GH) was derived from human cadavers; …
What is Solriamfetol Solriamfetol is a dopamine and norepinephrine reuptake inhibitor approved to improve wakefulness in adults with excessive daytime sleepiness associated with narcolepsy or obstructive sleep apnea. In patients with obstructive sleep apnea, the underlying airway obstruction should be treated (e.g., with CPAP) for at least 1 month prior to initiating solriamfetol. Increases in …
What is Solifenacin Solifenacin is an oral, competitive, selective M3 muscarinic antagonist indicated for the treatment of overactive bladder (OAB) and the associated symptoms of OAB is approved in adults and children 2 years and older. Brand Name VESIcare Indications & Dosage neurogenic bladder overactive bladder (OAB) urinary incontinence Side Effects abdominal pain anaphylactoid reactions …
What is Sofosbuvir Velpatasvir Voxilaprevir combination medicine Sofosbuvir Velpatasvir Voxilaprevir is an oral fixed-dose combination antiviral indicated for the treatment of chronic hepatitis C virus (HCV) infection in certain treatment-experienced adults without cirrhosis or who have compensated cirrhosis (Child-Pugh A). The drug is indicated for the treatment of HCV genotypes 1, 2, 3, 4, 5, …