What is Spironolactone Spironolactone is a potassium-sparing diuretic. In patients with severe heart failure (NYHA Class IV), spironolactone has been shown to improve overall survival and NYHA functional class, and to reduce hospitalizations when added to conventional therapy (e.g., ACE inhibitor, loop diuretic, digoxin). It is frequently used to treat ascites associated with cirrhosis and …
What is Spirapril NOTE: Not currently available in the US. Spirapril is an oral angiotensin-converting enzyme inhibitor. It is a carboxyl-containing ACE inhibitor, similar to ramipril and benazepril. Spirapril is a prodrug which is rapidly absorbed and hydrolyzed to an active diacid, spiraprilat. Spiraprilat has a short plasma half-life, but a prolonged duration of ACE …
What is Spinosad Spinosad is a topical product used for the treatment of head lice infestations. Spinosad is derived from the fermentation of a soil actinomycete bacterium, Saccharopolyspora spinosa. In premarketing clinical trials, patients were randomized to treatment with either spinosad or permethrin 1% and were reevaluated 7 days after treatment. If live lice were still …
What is Spectinomycin Spectinomycin is an intramuscular aminocyclitol antibiotic produced by Streptomyces spectabilis, a soil microorganism. It is used clinically as an alternative therapy for the treatment of acute gonorrheal urethritis in males and acute gonorrheal cervicitis and proctitis in females. Spectinomycin should not be used to treat pharyngeal gonorrhea due to the high rate of …
What is Sparfloxacin Description NOTE: This drug is discontinued in the US. Description: Sparfloxacin is an oral fluoroquinolone antibiotic approved for the treatment of community-acquired pneumonia and acute bacterial exacerbations of chronic bronchitis. Sparfloxacin is less active than ciprofloxacin against Pseudomonas aeruginosa and some other gram-negative bacilli. Sparfloxacin has a longer half-life than ciprofloxacin and can be administered …
What is Soy Isoflavones Soy isoflavones are phenolic phytoestrogens extracted from the soybean, Glycine max, a member of the legume family. The soy isoflavones are present in the plant as glycosides; once ingested, they yield the active isoflavonoids daidzein, genistein, and glycetin. Foods such as tofu, tempeh, miso, textured vegetable protein, soy milk and soy cheese …
What is Sotalol Sotalol is a hydrophilic, nonselective beta-adrenergic blocking agent, with low lipid-solubility. It is used to treat ventricular and supraventricular arrhythmias. Indications & Dosage atrial fibrillation atrial fibrillation prophylaxis atrial flutter cardiac surgery junctional ectopic tachycardia paroxysmal atrial tachycardia paroxysmal supraventricular tachycardia (PSVT) supraventricular arrhythmias ventricular tachycardia Wolff-Parkinson-White (WPW) syndrome Side Effects abdominal …