What is Rifapentine Rifapentine is a rifamycin derivative. It was originally developed in the 1950s, but was never marketed in the US until 1998. Rifapentine has a similar profile of microbiological activity to rifampin, but with a longer half-life. Its longer half-life allows for twice weekly dosing which was equivalent to daily dosing of rifampin. …
What is Rifamycin Rifamycin is an oral ansamycin class antibacterial drug indicated for treatment of traveler’s diarrhea caused by noninvasive strains of Escherichia coli (E. coli), not complicated by fever or blood in the stool. Rifamycin is minimally absorbed; therefore, systemic concentrations are generally below the level of detection. Clinically relevant drug interactions are not expected. The …
What is Rifampin Rifampin (rifampicin), a semisynthetic rifamycin antibiotic, is primarily used as part of first-line, combination therapy in the treatment of tuberculosis. Rifampin is also used to treat asymptomatic carriers of Neisseria meningitidis; as prophylaxis against Haemophilus influenzae type b in high-risk contacts; and in the treatment of rare diseases such as Hansen’s disease (leprosy), bartonellosis, and …
What is Rifabutin Rifabutin is an oral antimycobacterial agent. A derivative of rifamycin, rifabutin has been shown to be effective as a prophylactic agent against disseminated M. avium complex in patients with AIDS. Rifabutin is recommended as an alternative to clarithromycin or azithromycin for primary Mycobacterium avium complex prophylaxis in HIV-infected patients. Rifabutin is also considered an alternative to …
What is Riboflavin (Vitamin B2) Riboflavin, or vitamin B2, is a water-soluble vitamin found in such foods as milk, meat (especially liver and kidney), eggs, nuts, enriched flour, and green vegetables. Whole grains and cereals are not good sources. It is used to treat and prevent vitamin B2 deficiency, although a true riboflavin-deficiency disease state has …
What is Ribociclib and Letrozole combination medicine Ribociclib is an oral, selective inhibitor of cyclin-dependent kinases (CDKs) 4 and 6, which are both involved in tumor cell progression during phase G1 to phase S in the cell cycle. By inhibiting CDK 4 and 6, ribociclib prevents the deactivation of a tumor suppressor protein (retinoblastoma susceptibility …
What is Ribociclib Ribociclib is an oral, selective inhibitor of cyclin-dependent kinases (CDKs) 4 and 6, which are both involved in tumor cell progression during phase G1 to phase S in the cell cycle. By inhibiting CDK 4 and 6, ribociclib prevents the deactivation of the tumor suppressor protein known as retinoblastoma susceptibility gene protein, …