What is Tecovirimat Tecovirimat is an antiviral drug, and the first medication approved for treatment of human smallpox disease caused by the variola virus. Tecovirimat targets a virus specific protein (i.e., p37 envelope wrapping protein), and thus, possesses selective antiviral activity against orthopoxviruses, including variola virus. By blocking the actions of viral p37 protein, tecovirimat …
What is Tbo Filgrastim Tbo- filgrastim is a leukocyte growth factor that binds to cell surface receptors on hematopoietic cells stimulating proliferation, differentiation, commitment, and end cell functional activation. It is indicated to decrease the duration of neutropenia in patients aged 1 month and older with non-myeloid malignancies receiving myelosuppressive anticancer drugs associated with a …
What is Tazemetostat Tazemetostat is an EZH2 histone methyltransferase inhibitor indicated for the treatment of adults and pediatric patients aged 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. Tazemetostat therapy increases the risk of developing a new primary malignancy Brand Name TAZVERIK Indications soft-tissue sarcoma Side Effects …
What is Tazarotene Tazarotene is a retinoid prodrug of tazarotenic acid for the treatment of psoriasis, acne vulgaris, and photoaging of the skin. As vitamin A (retinol) derivatives, retinoids are important regulators of cell reproduction and cell proliferation and differentiation; however, unlike vitamin A, retinoids are not converted into rhodopsin, which is needed for night …
What is Tavaborole Tavaborole is an oxaborole antifungal indicated for the topical treatment of onchomycosis of the toenails caused by Trichophyton rubrum and Trichophyton mentagrophytes. Approval was based on the results of two randomized, double-blind, vehicle-controlled clinical trials involving adults with onychomycosis of the toenail (baseline clinical involvement of the target toenail ranged from 20—60%). In these trials, …
What is Tasimelteon Tasimelteon, a melatonin receptor agonist, is used for the treatment of non-24-hour sleep-wake disorder (non-24) in patients that are completely blind and have difficulties falling asleep, staying asleep, or who feel drowsy upon wakening. Non-24 is a chronic circadian rhythm disorder that occurs in blind patients because they cannot synchronize their circadian …
What is Tapentadol Tapentadol is an oral opioid agonist indicated for severe pain. It activates the mu-opioid receptor and inhibits norepinephrine synaptic reuptake. Norepinephrine reuptake inhibition appears to have additive analgesic effect to that of the drug’s opioid activity. Because no metabolic activation appears to be necessary for analgesia and no active metabolites have been …