What is Triamterene Triamterene is a potassium-sparing, distal tubule diuretic. It is similar in action to amiloride, but triamterene increases the urinary excretion of magnesium while amiloride does not. Triamterene is a relatively weak diuretic and antihypertensive and is most often used in the management of hypokalemia, especially in patients who cannot tolerate or have …
What is Triamcinolone Triamcinolone is a synthetic glucocorticoid that is considered slightly more potent than prednisone when given orally. Triamcinolone has little mineralocorticoid activity and is therefore not used systemically to manage adrenal insufficiency unless a more potent mineralocorticoid is administered concomitantly. Triamcinolone is commercially available in nasal, parenteral, topical, and intravitreal injection formulations. Oral …
What is Tretinoin (all trans retinoic acid ATRA) Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A. As vitamin A (retinol) derivatives, retinoids are important regulators of cell reproduction, and cell proliferation and differentiation; however, unlike vitamin A, retinoids are not converted into rhodopsin, which is needed for night …
What is Treprostinil Treprostinil is a tricyclic benzidine analog of epoprostenol (prostacyclin) approved for patients with pulmonary arterial hypertension (PAH; WHO Group I). Studies that established effectiveness in PAH treatment included predominately patients with New York Heart Association (NYHA) Class II to IV symptoms, Class III symptoms, and Class II to III symptoms for treprostinil …
What is Trazodone Trazodone is an oral antidepressant, unrelated to tricyclic or tetracyclic antidepressants. It possesses some similarities of action to other antidepressant drugs, however, and also has some action as an anxiolytic. Trazodone is used in the treatment of major depression, generalized anxiety disorder, and insomnia. Trazodone was approved by the FDA in 1981. …
What is Travoprost Travoprost, a synthetic analog of prostaglandin F2alpha, is a prodrug used to treat elevated intraocular pressure (IOP). The active component, travoprost free acid, is a selective FP prostanoid receptor agonist. Travoprost is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. When studied as add-on …
What is Trastuzumab and Hyaluronidase combination medicine Trastuzumab and hyaluronidase oysk is a combination of trastuzumab, a HER2/neu receptor antagonist, and hyaluronidase, an endoglycosidase indicated for the treatment of HER2-overexpressing breast cancer in adults. Use should be limited to patients with documented overexpression of the HER2 protein, using FDA-approved tests specific for breast cancer; gene …