Deferoxamine Brand Name– Desferal What is Deferoxamine Deferoxamine is an iron-chelating agent used in the treatment of acute iron intoxication and chronic iron overload secondary to multiple RBC transfusions (i.e., transfusional iron overload) in patients requiring multiple RBC transfusions such as those with thalassemia, sickle cell anemia, or other chronic anemias. Initially produced as a …
Deferiprone Brand Name– FERRIPROX What is Deferiprone Deferiprone is an iron chelator approved for the treatment of transfusional iron overload due to thalassemia syndromes when current chelation therapy is inadequate. Iron overload is a serious complication caused by frequent blood transfusions in patients with blood transfusion-dependent anemias, such as ß-thalassemia. In patients with chronic iron …
Deferasirox Brand Names- Exjade | JADENU What is Deferasirox Deferasirox is a first in class, tridentate, oral, iron-chelating agent used in the treatment of chronic iron overload secondary to multiple RBC transfusions (i.e., transfusional iron overload) and non-transfusion dependent thalassemia syndromes. Iron overload is a serious complication caused by frequent blood transfusions in patients with blood …
Decitabine Brand Name– Dacogen What is Decitabine Decitabine is a pyrimidine antimetabolite. It is indicated for the treatment of adult patients with myelodysplastic syndrome. Severe myelosuppression has been reported with decitabine therapy; monitor complete blood counts during therapy Indications acute myelogenous leukemia (AML) chronic myelogenous leukemia (CML) myelodysplastic syndrome (MDS) For the treatment myelodysplastic syndrome …
Daunorubicin Liposomal Cytarabine Liposomal Brand Name– VYXEOS What is Daunorubicin Liposomal Cytarabine Liposomal Daunorubicin liposomal cytarabine liposomal is a combination of daunorubicin and cytarabine in a 1:5 molar ratio encapsulated in liposomes. It is approved for the treatment of adult patients with newly diagnosed therapy-related AML or AML with myelodysplasia-related changes. Daunorubicin liposomal cytarabine liposomal …
Daunorubicin Liposomal Brand Name– DaunoXome What is Daunorubicin Liposomal DaunoXome incorporates daunorubicin, an anthracycline chemotherapy agent, into a liposomal carrier. It has been developed to decrease the incidence of severe toxicity seen with the conventional formulation of daunorubicin while taking advantage of the unique delivery properties of liposomes and the cytotoxic effects of daunorubicin. DaunoXome(R) …
Daunorubicin Brand Name– Cerubidine What is Daunorubicin Daunorubicin is an anthracycline chemotherapy agent indicated in combination with other anticancer agents for remission induction in acute nonlymphocytic leukemias (e.g., myelogenous, monocytic, and erythroid) in adults and for remission induction in acute lymphocytic leukemia in pediatric and adult patients. Dose-limiting cardiotoxicity and myelosuppression have been reported with …