Ofloxacin Brand Names- Floxin | Ocuflox What is Ofloxacin Ofloxacin is an oral, otic, and ophthalmic fluoroquinolone anti-infective. Its half-life is intermediate between norfloxacin and lomefloxacin. In general, ofloxacin is less potent than ciprofloxacin against most gram-negative bacteria. Disabling and potentially irreversible serious adverse reactions associated with quinolones include tendinitis, tendon rupture, peripheral neuropathy, and central …
Ofatumumab Brand Name– Arzerra What is Ofatumumab Ofatumumab is a fully human monoclonal antibody that binds specifically to the CD20 molecule expressed on normal B lymphocytes and on B-cell chronic lymphocytic leukemia (CLL), which causes B-cell lysis and death. The epitope that ofatumumab binds is different from the binding sites targeted by other CD20 antibodies …
Octreotide Brand Names Bynfezia | Mycapssa | Sandostatin | Sandostatin LAR What is Octreotide Octreotide is a synthetic analog of the naturally occurring hormone somatostatin. The activity of octreotide is similar to that of somatostatin. Octreotide, however, has a longer half-life, greater selectivity for inhibiting glucagon, growth hormone, and insulin release, and a lower incidence of rebound hypersecretion …
Ocriplasmin Brand Name– JETREA What is Ocriplasmin Ocriplasmin is a proteolytic enzyme approved for the treatment of symptomatic vitreomacular adhesion (VMA). Ocriplasmin is administered via ophthalmic intravitreal injection only. This is the first drug to receive FDA-approval for the treatment of VMA. Ocriplasmin (Jetrea) was approved by the FDA in October 2012. Indications vitreomacular adhesion …
Ocrelizumab Brand Name– OCREVUS What is Ocrelizumab Ocrelizumab is an intravenous CD20-directed cytolytic monoclonal antibody that targets and depletes B cells. B cell activation contributes to CNS damage in MS patients. Ocrelizumab was the first B-cell targeted therapy FDA-approved for MS in adult patients and is used for relapsing forms of primary progressive MS and …
Obinutuzumab Brand Name– GAZYVA What is Obinutuzumab Obinutuzumab is a monoclonal antibody that binds to the CD20 molecule found on pre B- and mature B-lymphocytes. It is indicated for the treatment of previously untreated chronic lymphocytic leukemia in combination with chlorambucil; relapsed or refractory follicular lymphoma (FL) in combination with bendamustine; and previously untreated bulky …
Obiltoxaximab Brand Name– Anthim What is Obiltoxaximab Obiltoxaximab is a monoclonal antibody that neutralizes toxins produced by Bacillus anthracis for the treatment of inhalational anthrax in combination with appropriate antibacterial drugs or when alternative therapies are not available or not appropriate in adult and pediatric patients. Obiltoxaximab was approved under the FDA’s Animal Efficacy Rule, which allows …