Olsalazine Brand Name– Dipentum What is Olsalazine Olsalazine is an oral diazo-bonded 5-aminosalicylate (5-ASA) and is a prodrug; bacterial azoreduction in the intestines releases the anti-inflammatory agent mesalamine (5-ASA) to produce the active effect. Olsalazine is used for the maintenance of remission in patients with ulcerative colitis (UC) who are intolerant to sulfasalazine. The guidelines …
Olopatadine Brand Names Pataday | Patanase | Patanol | Pazeo What is Olopatadine Olopatadine is a topical antihistamine with selective H1-receptor antagonist activity and mast cell stabilizing effects. It is marketed as an ophthalmic agent for the prevention of ocular pruritus due to allergic conjunctivitis and as a nasal spray for the relief of the symptoms of seasonal …
Olodaterol Brand Name– Striverdi Respimat What is Olodaterol Olodaterol is an inhaled long-acting beta-2 adrenergic agonist (LABA) that is given once daily. It is indicated for the maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD). According to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines for COPD, LABAs …
Olmesartan Brand Name– Benicar What is Olmesartan Olmesartan is an angiotensin II receptor antagonist, indicated for the treatment of hypertension. Compared to other angiotensin II receptor antagonists, olmesartan medoxomil is a prodrug which is administered orally and converted to olmesartan during gastrointestinal absorption. Olmesartan does not undergo further metabolism by the liver, lacks cytochrome P-450 …
Olaratumab Brand Name– LARTRUVO What is Olaratumab Olaratumab is a human monoclonal antibody that binds platelet-derived growth factor receptor-alpha (PDGFR-alpha). It is indicated in combination with doxorubicin for the treatment of soft tissue sarcoma not amenable to curative treatment with radiotherapy or surgery. The median progression-free survival and overall survival times were significantly improved in …
Olaparib Brand Name– Lynparza What is Olaparib Olaparib is an oral poly (ADP-ribose) polymerase (PARP) inhibitor. PARP enzymes are involved in normal cellular homeostasis, including DNA transcription, cell cycle regulation, and DNA repair. Increased cytotoxicity and anti-tumor activity has been noted in cell lines and mouse tumor models with deficiencies in BRCA. It is approved …
Olanzapine Brand Names Zyprexa | Zyprexa Intramuscular | Zyprexa Relprevv | Zyprexa Zydis What is Olanzapine Olanzapine is an atypical antipsychotic similar in chemical structure and mechanism of action to clozapine, but with a lower incidence of side effects, including neutropenia. Atypical antipsychotics (excluding clozapine) are deemed to be the standard of care for schizophrenia and related disorders. …