Drugs

Moexipril

Moexipril Brand Name– Univasc What is Moexipril Moexipril is classified as an oral angiotensin-converting enzyme (ACE) inhibitor and is used to treat hypertension. Like quinapril and ramipril, the active moiety of moexipril is produced by deesterification from the prodrug. Moexiprilat, is about 1000 times more potent than its prodrug moexipril. Prolonged antihypertensive effects allow for …

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Modafinil

Modafinil Brand Name– Provigil What is Modafinil Modafinil is a racemic compound with unique properties in promoting wakefulness; modafinil’s mechanism of action appears to be distinct from that of other CNS stimulants. The potential for abuse liability with modafinil is apparently lower than that of other controlled stimulants, though still present. In clinical trials for …

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Mivacurium

Mivacurium Brand Name– Mivacron What is Mivacurium Mivacurium is a parenteral, short-acting, nondepolarizing, neuromuscular blocking agent (NMBA) indicated as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Mivacurium undergoes hydrolysis via plasma cholinesterase similar to succinylcholine but at only 88% the rate; this …

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Mitoxantrone

Mitoxantrone Brand Name– Novantrone What is Mitoxantrone Mitoxantrone is a parenteral, synthetic antineoplastic agent. Chemically, it is an anthracenedione and is structurally similar to the anthracyclines, doxorubicin, daunorubicin and idarubicin. Mitoxantrone is sometimes substituted for doxorubicin or daunorubicin because it has considerably less cardiotoxicity and mitoxantrone is not a vesicant as are the other anthracyclines. …

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Mitotane

Mitotane Brand Name– Lysodren What is Mitotane Mitotane is an adrenocortical cytotoxic antineoplastic agent that is structurally related to the insecticide chlorophenothane (DDT). It is used almost exclusively for adrenocortical carcinoma but also could be useful in Cushing’s disease. It appears to act by impairing steroid synthesis, which in turn causes adrenal atrophy. Mitotane was …

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Mitomycin

Mitomycin Brand Name– JELMYTO | Mitosol | Mutamycin What is Mitomycin Mitomycin is an antitumor antibiotic that acts as an alkylating agent and is derived from Streptomyces caespitosus. It is indicated intravenously for the treatment of metastatic stomach or pancreatic cancer in proven combinations with other chemotherapeutic agents. An ophthalmic solution is indicated as a topical adjunct …

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