Acute Biphenotypic Leukemia (BAL)

What is Acute Biphenotypic Leukemia (BAL)

BAL is a rare type of leukaemia.

Biphenotypic acute leukemia is a combination of two types of acute leukemias, they are acute myeloid leukaemia (AML) and acute lymphoblastic leukaemia (ALL).


The exact cause of BAL is unknown

Prognosis of BAL

  • Prognosis of Acute Biphenotypic Leukemia is poor.
  • But recent research conducted reveal that there are some good prognostic features
  • Here are the most important emerging factors indicating good prognosis are:
  • individuals less than age of 60
  • absence of the Philadelphia chromosome


  • Treatment depends on the most common type of immature blood cells or blasts (AML or ALL) in the leukemia
  • Chemotherapy
  • Bone marrow transplant