Time course of alcohol withdrawal symptoms

Time course of alcohol withdrawal symptoms

What is the time course of signs and symptoms of alcohol withdrawal

Time Course and Associated Signs and Symptoms of Alcohol Withdrawal

Time Course: Onset ∗ /DurationSigns and Symptoms
Early: 6 hr/2 daysAnxiety, tremor, palpitations, nausea, anorexia
6-48 hr/3 daysSeizures
12-48 hr/2 daysAlcoholic hallucinosis (visual, auditory, tactile hallucinations with intact sensorium)
Late: 48-96 hr/5 daysDelirium tremens (deficit in awareness and attention (impaired sensorium); often with agitation, tremor, hallucinations, autonomic hyperactivity, and abnormal movements (parkinsonism, chorea, dystonia, myoclonus) and catatonia

∗ Onset is time since last drink.

Sources

Adapted from Tetrault JM, O’Connor PG. Substance abuse and withdrawal in the critical care setting. Crit Care Clin 24(4):767–788 (Table 2), 2008; Brust JCM: Acute withdrawal: diagnosis and treatment. In Sullivan EV, Pfefferbaum A, editors. Handbook of Clinical Neurology, vol. 125 (3rd series) Alcohol and the Nervous System, Elsevier BV; pp. 123–131. 2014.

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