Most common causes of amnestic syndromes

What are the most common causes of amnestic syndromes? 

The etiologies for amnestic syndromes can be divided according to their anatomic location:

  • Medial temporal lobes—hypoxia, herpes simplex encephalitis, early AD, posterior cortical atrophy (PCA), strokes (thalamic and temporal lobe), surgery
  • Diencephalon—Korsakoff’s syndrome (thiamine deficiency), thalamic strokes, surgery
  • Basal forebrain—anterior communicating artery aneurysm bleed or clipping (with damage to the small perforating arteries)
  • Substances—alcohol, benzodiazepines (transient, not permanent)

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