Is male fertility affected by rheumatic disease

Is male fertility affected by rheumatic disease?

• Vasculitis: decreased fertility if testicular involvement in PAN; patients with Behçet’s disease have normal fertility. Data is lacking for other forms of vasculitis.

• Ankylosing spondylitis: higher rates of varicocele, but no other changes in sperm.

• RA: active RA is associated with hypogonadism as well as decreased sperm production and function.

• SLE: decreased libido, erectile dysfunction, and failure to ejaculate, though it is difficult to sort out medication effect.

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