Where is clinical jaundice first visible

Where is clinical jaundice first visible? 

The mucosae of the soft palate and sublingual region are often the first mucocutaneous surfaces to appear yellow in response to hyperbilirubinemia.

This is likely because of the thin mucosal surface in these anatomic locations. Bilirubin also has a strong affinity for elastin, which accounts for its early appearance in the sclera of the eye.


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