Chlamydia trachomatis a, Ureaplasma urealyticum b, Mycoplasma genitalium b
Enterogenic
Salmonella atyphimurium, S. enteritidis, S. heidelberg, S. cholerae-suis
Shigella aflexneri, S. dysenteriae, S. sonnei
Yersinia a(especially O:3 and O:9), Y. pseudotuberculosis
Campylobacter ajejuni, C. Coli
Clostridium difficile b
Escherichia coli b, Diarrhogenic strains
Giardia lamblia b
Respiratory
Chlamydia pneumoniae b
Group A beta-hemolytic Streptococcus b , c
Viral
Human immunodeficiency virus b , d
Multiple sources, case reports only e
Helicobacter pylori
Vibrio parahaemolyticus
Mycobacterium bovis
Calmette-Guerin Bacillus
Klebsiella pneumonia
Strongyloides stercoralis
Note: In up to 40% of ReA patients, an infectious agent cannot be identified. Serologic tests especially for Chlamydia may identify a previous infection if cultures/PCR are negative.
a Common infections associated with ReA. Also, most common infections associated with HLA-B27-patients.
b Uncommon infections associated with ReA.
c Typically causes acute rheumatic fever, but has been described to cause ReA.
d ReA has occurred in the setting of HIV, but usually the virus is not directly associated and other pathogens may be implicated.
