What drugs are effective as chronic immunosuppressives in Myasthenia gravis?
Oral prednisone is the single most effective treatment for Myasthenia gravis, resulting in dramatic improvement in 90% of cases within 4 weeks.
Azathioprine and mycophenolate are also often effective as sole agents but take longer to begin to work (3 to 6 months).
They have a primary role as adjunctive therapy for patients in whom steroids cannot be effectively tapered, and may be drugs of first choice in patients with mild, nonprogressive disease.
Methotrexate, cyclosporine, rituximab, eculizumab, and cyclophosphamide may also be of benefit.