What diseases are associated with decreased levels of complement (not hereditary deficiency)?
• Rheumatic diseases
– SLE
– Systemic vasculitis (especially polyarteritis nodosa, urticarial vasculitis)
– Cryoglobulinemia (types II and III)
– RA with extraarticular manifestations (rare)
• Infectious diseases
– Subacute bacterial endocarditis
– Bacterial sepsis (pneumococcal, gram-negative)
– Viremias (especially hepatitis B)
– Parasitemias
• Glomerulonephritis
– Post-streptococcal
– Membranoproliferative
