What diseases are associated with decreased levels of complement

What diseases are associated with decreased levels of complement (not hereditary deficiency)?

• Rheumatic diseases

– SLE

– Systemic vasculitis (especially polyarteritis nodosa, urticarial vasculitis)

– Cryoglobulinemia (types II and III)

– RA with extraarticular manifestations (rare)

• Infectious diseases

– Subacute bacterial endocarditis

– Bacterial sepsis (pneumococcal, gram-negative)

– Viremias (especially hepatitis B)

– Parasitemias

• Glomerulonephritis

– Post-streptococcal

– Membranoproliferative

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