What is the most common cause of traveler’s diarrhea?
ETEC infection is the most common identified cause of traveler’s diarrhea in most of the world. ETEC strains cause a watery diarrhea syndrome of varying severity resulting from the production of one or two enterotoxins: heat-stable toxin and heat-labile toxin (LT). The LT variant is closely related to cholera toxin and results in profuse, watery diarrhea. Other diarrheagenic E. coli (EAEC), Campylobacter, Shigella, and Salmonella infections are common as well. Viral and parasitic infection cause a minority of episodes.