Variant of unknown significance (VUS)

Variant of unknown significance (VUS)

A VUS is an alteration in the normal or reference sequence of a gene that has no known effect on the gene function or no known association with disease risk.

The significance of a VUS is unclear until additional studies clarify its biologic significance in a sufficiently large population.

Gene sequencing studies such as whole exome sequencing often identify numerous allelic variants in many genes.

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856
Scroll to Top