Treatment for complications of Pagets Disease of Bone

Treatment for complications of Pagets Disease of Bone

What other treatments should be considered for patients with complications from PDB?

Pain due to secondary OA in PDB may be effectively treated with traditional analgesics like acetaminophen or nonsteroidal antiinflammatory drugs. Medications such as gabapentin, pregabalin, and amitriptyline can be used if neuropathic pain is present. Other treatment modalities may include orthopedic surgery to correct bone deformities, address spinal canal stenosis, or to treat pseudofractures. Canes and shoe lifts can be helpful for patients with limb deformities. It is also important for patients to have adequate calcium and vitamin D levels to avoid hypocalcemia, especially if planning for IV bisphosphonate treatment.

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