Syndrome of acute glomerulonephritis?
Acute glomerulonephritis is an acute kidney injury (AKI) syndrome characterized by the sudden onset of edema and new-onset or worsening hypertension.
Urinalysis demonstrates an active sediment, including abnormal proteinuria (usually >30 mg/dL or 1+ on a semiquantitative scale), hematuria, and red cell casts. Patients with acute glomerulonephritis are often azotemic (i.e., they have elevated serum blood urea nitrogen and creatinine concentrations) and occasionally develop severe kidney injury requiring dialysis.
Acute glomerulonephritis can be a primary kidney disease, which is usually classified on the basis of kidney histopathology, or can result from a number of systemic diseases.
The reader is referred to the sections on primary (Part IV) and secondary (Part V) glomerular disorders for additional information.