Risks of gadolinium

Sharing is caring!

Risks of gadolinium

What is gadolinium and what risks are associated with it?

Gadolinium is a lanthanide metal with paramagnetic properties, making it a suitable contrast agent. Initially, it was assumed to be a safe alternative to iodinated contrast; however, subsequently, it was shown to cause nephrogenic systemic fibrosis (NSF) in patients on dialysis or with severe impairment of kidney function.

NSF is a severe fibrosing disorder of the skin and other organs that can be debilitating and fatal. The majority of cases of NSF occur in patients with end-stage kidney disease who were receiving renal replacement therapy. No cases have been reported with stage 1 to 3 CKD, and only a few cases with CKD 4. If gadolinium must be administered in patients with advanced CKD, experts recommend:

• Using a macrocyclic ionic chelate-based gadolinium rather than linear nonionic type

• Administering the lowest dosage possible

• Avoiding repeated exposures

• Consider hemodialysis after gadolinium administration.

• Due to the risk of NSF in patients at high-risk for CIN, gadolinium contrast media cannot be recommended for the reduction of CIN risk.

Sharing is caring!

You cannot copy content of this page


Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

Scroll to Top