Symptoms of Contrast induced nephropathy
What are the clinical features of Contrast induced nephropathy?
Contrast induced nephropathy usually manifests with Acute Kidney Injury developing within 24 to 48 hours, with peak injury anywhere between 72 and 120 hours after insult. It may take 7 to 10 days before serum creatinine returns to baseline.
How is Contrast induced nephropathy diagnosed?
The injury typically does not cause proteinuria, and the urinalysis resembles acute tubular necrosis with muddy brown casts and renal tubular epithelial cells.
The fractional excretion of sodium is typically below 1%, which presumably is due to the severe vasoconstriction, although the significance of this is confounded in that Contrast induced nephropathy is almost always non-oliguric.
Kidney biopsy is not indicated unless the presentation is atypical and the diagnosis is unclear.