Symptoms in females with Alport syndrome
What are the major clinical findings in females with Alport syndrome?
Females with Alport syndrome have a much milder course than do males, but should be characterized as “affected individuals” rather than “carriers” who have an “at risk” state. Microscopic hematuria is present in 95% of females, but significant proteinuria and progressive kidney dysfunction occur in 15% of females by the age of 60 years.
