Silicone synovitis

What is silicone synovitis?

Silicone-containing joint implants have been used to replace the metacarpophalangeal (MCP), PIP, first metatarsophalangeal, and wrist joints. Wear particles from fracturing of the prosthesis can be ingested by macrophages generating an inflammatory response, leading to a destructive synovitis. This occurs most commonly with wrist implants. Patients who develop this condition receive NSAIDs for symptom control but frequently require removal of the prosthesis and synovectomy.


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