Side effects of PD 1 and PD L1 inhibitors

What is the most frequently reported adverse event with PD-1 and PD-L1 inhibitors?

Fatigue is the most commonly reported AE with these agents, and the pathogenesis is poorly understood. Individual drug studies report fatigue in 16% to 37% of patients on PD-1 inhibitors and 12% to 24% of patients on PD-L1 inhibitors. Of the patients who report fatigue with these agents, only a minority will have hypothyroidism as a cause. Regardless, patients with even subtle changes in their energy level should have adrenal and thyroid laboratory values assessed to evaluate for potential endocrinopathies.

15585

Sign up to receive the trending updates and tons of Health Tips

Join SeekhealthZ and never miss the latest health information

15856
Scroll to Top